Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

Understanding the molecular foundation for immune recognition of SARS-CoV-2 spike glycoprotein antigenic websites will inform the event of improved therapeutics. We decided the buildings of two human monoclonal antibodies-AZD8895 and AZD1061-which kind the idea of the investigational antibody cocktail AZD7442, in complicated with the receptor-binding area (RBD) of SARS-CoV-2 to outline the genetic and structural foundation of neutralization. AZD8895…

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