Assay Kits Biology Cells cDNA DNA DNA Templates Elisa Kits Equipments Exosomes Isotypes Panel Particles PCR Reagents Recombinant Proteins Test Kits Western Blot
Caffeine consumption, toxicity, tolerance and withdrawal; shared genetic influences with normative personality and personality disorder traits
Our most important intention was to estimate the extent of overlapping etiology between caffeine consumption and response and normative and pathological character. Linear mixed-effects fashions had been used to determine normative character domains and character dysfunction (PD) traits for inclusion in multivariate twin analyses along with particular person caffeine associated measures. Information had been obtained from Norwegian grownup twins in a face-to-face interview carried out in 1999-2004 as a part of a population-based examine of psychological well being and thru self-report in 2010-2011 and 2015-2017. Persona dysfunction knowledge was obtainable for two,793 twins, normative character for 3,889 twins, and caffeine for 3,862 twins (imply age 43.Zero years). Normative character was assessed utilizing the self-reported Large 5 Stock, PD traits had been assessed by the Structured Interview for DSM-IV Persona, and caffeine consumption, toxicity, tolerance, and withdrawal had been assessed by way of a self-report questionnaire developed on the Norwegian Institute of Public Well being.
Caffeine measures had been discovered to be reasonably heritable, h2 = 30.1%-45.0%. All normative character domains and 4 PD traits, delinquent, borderline, dependent and paranoid, had been considerably related to at the least one caffeine variable. A small proportion of variance in caffeine consumption was attributable to genetic components shared with normative character (1.3%) and character issues (11.4%). A modest proportion of variance in caffeine tolerance and toxicity was attributable to genetic components shared with each normative character (26.9%, 24.8%) and character issues (21.0%, 36.0%). The current examine discovered caffeine consumption and response to be heritable and offers proof {that a} small to-modest proportion of this genetic etiology is shared with each normative and pathological character.
Blood-brain barrier genetic disruption results in protecting barrier formation on the Glia Limitans
Irritation of the central nervous system (CNS) induces endothelial blood-brain barrier (BBB) opening in addition to the formation of a decent junction barrier between reactive astrocytes on the Glia Limitans. We hypothesized that the CNS parenchyma might purchase safety from the reactive astrocytic Glia Limitans not solely throughout neuroinflammation but additionally when BBB integrity is compromised within the resting state. Earlier research discovered that astrocyte-derived Sonic hedgehog (SHH) stabilizes the BBB throughout CNS inflammatory illness, whereas endothelial-derived desert hedgehog (DHH) is expressed on the BBB underneath resting circumstances.
Right here, we investigated the consequences of endothelial Dhh on the integrity of the BBB and Glia Limitans. We first characterised DHH expression inside endothelial cells on the BBB, then demonstrated that DHH is down-regulated throughout experimental autoimmune encephalomyelitis (EAE). Utilizing a mouse mannequin through which endothelial Dhh is inducibly deleted, we discovered that endothelial Dhh each opens the BBB by way of the modulation of forkhead field O1 (FoxO1) transcriptional exercise and induces a decent junctional barrier on the Glia Limitans. We confirmed the relevance of this glial barrier system in human a number of sclerosis lively lesions.
These outcomes present proof for the novel idea of “power neuroinflammatory tolerance” through which BBB opening within the resting state is enough to stimulate a protecting barrier on the Glia Limitans that limits the severity of subsequent neuroinflammatory illness. In abstract, genetic disruption of the BBB generates endothelial indicators that drive the formation underneath resting circumstances of a secondary barrier on the Glia Limitans with protecting results towards subsequent CNS irritation. The idea of a reciprocally regulated CNS double barrier system has implications for remedy methods in each the acute and power phases of a number of sclerosis pathophysiology.
A Pilot Research of Identification Genetic Background of Craniosynostosis Circumstances in Turkey
The early fusion of the cranial sutures was described as a craniosynostosis. The early prognosis and administration of craniosynostosis is essential. Environmental components and genetic abnormalities performs a key position in the course of the growth of craniosynostosis. Syndromic craniosynostosis instances are associated with autosomal dominant issues however practically half of the affected instances carry a brand new mutation. On this examine, as a way to determine the genetic etiology of craniosynostosis the authors analyzed 20 craniosynostosis sufferers through the use of standard karyotype, aCGH, sanger sequencing, subsequent technology sequencing (NGS) and Multiplex ligation-dependent probe amplification (MLPA) strategies.
The authors recognized mutations on FGFR2 and FGFR3 genes which had been related to Muenke syndrome, Crouzon syndrome and skeletal dysplasia syndromes. NGS utilized the entire instances and seven medical variations in 5 completely different gene had been detected in %20 of instances. Along with these abnormalities; del(11)(q14.1q22.2), del(17)(q21.31), dup(22)(q13.31) and t(2;16)(q37;p13) have been recognized in our cohort which aren’t beforehand detected in craniosynostosis instances. Our examine demonstrates the significance of detailed genetic evaluation for the prognosis, development and administration of the craniosynostosis. Hopea hainanensis Merrill & Chun (Dipterocarpaceae) is an endangered tree species restricted to Hainan Island, China and a small a part of Northern Vietnam. On Hainan Island, it is a crucial indicator species for tropical forests.
Genome polyprotein Antibody |
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| 1-CSB-PA18549A0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Unconjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody |
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| 1-CSB-PA333180LA01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Unconjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody |
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| 1-CSB-PA362073LA01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Unconjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody |
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| 1-CSB-PA714772LA01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Unconjugated. Tested in the following application: ELISA |
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Genome Polyprotein Antibody (Biotin) |
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| 20-abx105887 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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| 20-abx106264 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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| 20-abx107678 | Abbexa |
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Genome polyprotein Antibody (HRP) |
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| 20-abx109095 | Abbexa |
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Genome Polyprotein Polyclonal Antibody |
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| A56130 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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Genome Polyprotein Polyclonal Antibody |
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| A56743 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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Genome polyprotein Antibody (HRP) |
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| 20-abx300968 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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| 20-abx300969 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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| 20-abx300970 | Abbexa |
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Genome Polyprotein Polyclonal Antibody |
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| A68253 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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Genome Polyprotein Polyclonal Antibody |
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| A68254 | EpiGentek | 100 µg | EUR 570.55 |
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Description: reagents widely cited |
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Enterovirus 71 Genome polyprotein Antibody |
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| 20-abx109758 | Abbexa |
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Genome Polyprotein (HCV-Core) Antibody |
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| 33487-05111 | AssayPro | 150 ug | EUR 261 |
Genome polyprotein Antibody, HRP conjugated |
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| 1-CSB-PA18549B0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is HRP conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, FITC conjugated |
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| 1-CSB-PA18549C0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is FITC conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, Biotin conjugated |
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| 1-CSB-PA18549D0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, HRP conjugated |
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| 1-CSB-PA333180LB01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is HRP conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, FITC conjugated |
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| 1-CSB-PA333180LC01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is FITC conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, Biotin conjugated |
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| 1-CSB-PA333180LD01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, HRP conjugated |
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| 1-CSB-PA362073LB01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is HRP conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, FITC conjugated |
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| 1-CSB-PA362073LC01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is FITC conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, Biotin conjugated |
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| 1-CSB-PA362073LD01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, HRP conjugated |
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| 1-CSB-PA714772LB01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is HRP conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, FITC conjugated |
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| 1-CSB-PA714772LC01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is FITC conjugated. Tested in the following application: ELISA |
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Genome polyprotein Antibody, Biotin conjugated |
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| 1-CSB-PA714772LD01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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Hepatitis C Genome polyprotein |
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| 1-CSB-RP184674Ba | Cusabio |
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Description: Recombinant Hepatitis C Genome polyprotein expressed in E.coli |
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Enterovirus 71 Genome polyprotein Antibody (FITC) |
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| 20-abx106801 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (HRP) |
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| 20-abx108220 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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| 20-abx105382 | Abbexa |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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| A56131 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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| A56132 | EpiGentek | 100 µg | EUR 570.55 |
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Description: kits suitable for this type of research |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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| A56133 | EpiGentek | 100 µg | EUR 570.55 |
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Description: fast delivery possible |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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| A56744 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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| A56745 | EpiGentek | 100 µg | EUR 570.55 |
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Description: kits suitable for this type of research |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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| A56746 | EpiGentek | 100 µg | EUR 570.55 |
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Description: fast delivery possible |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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| A68250 | EpiGentek | 100 µg | EUR 570.55 |
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Description: reagents widely cited |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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| A68251 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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| A68252 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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| A68255 | EpiGentek | 100 µg | EUR 570.55 |
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Description: Ask the seller for details |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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| A68256 | EpiGentek | 100 µg | EUR 570.55 |
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Description: The best epigenetics products |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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| A68257 | EpiGentek | 100 µg | EUR 570.55 |
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Description: kits suitable for this type of research |
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Human rhinovirus 1A Genome polyprotein |
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| 1-CSB-YP326367HQA | Cusabio |
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Description: Recombinant Human rhinovirus 1A Genome polyprotein,partial expressed in Yeast |
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Japanese encephalitis virus Genome polyprotein |
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| 1-CSB-EP189574Ba | Cusabio |
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Description: Recombinant Japanese encephalitis virus Genome polyprotein,partial expressed in E.coli |
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Yellow fever virus Genome polyprotein |
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| 1-CSB-EP365905YAC1 | Cusabio |
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Description: Recombinant Yellow fever virus Genome polyprotein,partial expressed in E.coli |
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Rhinovirus A serotype 89 Genome polyprotein Antibody |
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| 20-abx109372 | Abbexa |
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Genome Polyprotein (HCV-Core) Antibody (Biotin Conjugate) |
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| 33487-05121 | AssayPro | 150 ug | EUR 369 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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| 20-abx107303 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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| 20-abx108723 | Abbexa |
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Genome Polyprotein (HCV-Core) AssayLite Antibody (FITC Conjugate) |
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| 33487-05141 | AssayPro | 150 ug | EUR 428 |
Genome Polyprotein (HCV-Core) AssayLite Antibody (RPE Conjugate) |
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| 33487-05151 | AssayPro | 150 ug | EUR 428 |
Genome Polyprotein (HCV-Core) AssayLite Antibody (APC Conjugate) |
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| 33487-05161 | AssayPro | 150 ug | EUR 428 |
Genome Polyprotein (HCV-Core) AssayLite Antibody (PerCP Conjugate) |
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| 33487-05171 | AssayPro | 150 ug | EUR 471 |
Human rhinovirus A serotype 89 Genome polyprotein |
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| 1-CSB-YP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in Yeast |
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Hepatitis C virus genotype 1a Genome polyprotein |
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| 1-CSB-EP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in E.coli |
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Human rhinovirus A serotype 89 Genome polyprotein |
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| 1-CSB-EP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
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Human rhinovirus A serotype 89 Genome polyprotein |
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| 1-CSB-EP362073HQDb0 | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
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Hepatitis C virus genotype 1a Genome polyprotein |
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| 1-CSB-MP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in Mammalian cell |
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Hepatitis C virus genotype 1b Genome polyprotein |
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| 1-CSB-YP530838HVQ(A3) | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial expressed in Yeast |
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Hepatitis C virus genotype 1b Genome polyprotein |
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| 1-CSB-YP530838HVQ(A4) | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial expressed in Yeast |
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Recombinant Human Genome polyprotein, His, Yeast-100ug |
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| QP7370-ye-100ug | EnQuireBio | 100ug | EUR 480 |
Recombinant Human Genome polyprotein, His, Yeast-10ug |
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| QP7370-ye-10ug | EnQuireBio | 10ug | EUR 236 |
Recombinant Human Genome polyprotein, His, Yeast-1mg |
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| QP7370-ye-1mg | EnQuireBio | 1mg | EUR 1885 |
Recombinant Human Genome polyprotein, His, Yeast-200ug |
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| QP7370-ye-200ug | EnQuireBio | 200ug | EUR 744 |
Recombinant Human Genome polyprotein, His, Yeast-500ug |
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| QP7370-ye-500ug | EnQuireBio | 500ug | EUR 1206 |
Recombinant Human Genome polyprotein, His, Yeast-50ug |
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| QP7370-ye-50ug | EnQuireBio | 50ug | EUR 299 |
Recombinant JEV Genome polyprotein (aa 2528-3432) Protein |
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| VAng-Wyb3447-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 8272 |
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Description: Japanese encephalitis virus (strain Jaoars982) Genome polyprotein, recombinant protein. |
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Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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| VAng-Cr6541-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 4793 |
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Description: YFV Genome polyprotein, partial, recombinant protein. |
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Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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| VAng-Cr6541-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3048 |
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Description: YFV Genome polyprotein, partial, recombinant protein. |
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Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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| VAng-Cr6541-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 903 |
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Description: YFV Genome polyprotein, partial, recombinant protein. |
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Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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| VAng-Cr6542-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 2840 |
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Description: YFV Genome polyprotein, recombinant protein. |
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Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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| VAng-Cr6542-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2044 |
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Description: YFV Genome polyprotein, recombinant protein. |
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Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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| VAng-Cr6542-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1411 |
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Description: YFV Genome polyprotein, recombinant protein. |
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Recombinant Human Genome polyprotein, His-SUMO, E.coli-100ug |
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| QP7370-ec-100ug | EnQuireBio | 100ug | EUR 408 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-10ug |
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| QP7370-ec-10ug | EnQuireBio | 10ug | EUR 200 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-1mg |
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| QP7370-ec-1mg | EnQuireBio | 1mg | EUR 1632 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-200ug |
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| QP7370-ec-200ug | EnQuireBio | 200ug | EUR 634 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-500ug |
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| QP7370-ec-500ug | EnQuireBio | 500ug | EUR 1060 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-50ug |
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| QP7370-ec-50ug | EnQuireBio | 50ug | EUR 263 |
Recombinant YFV Genome polyprotein (NS4A) Protein (aa 1-3412) |
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| VAng-Cr6545-inquire | Creative Biolabs | inquire | Ask for price |
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Description: YFV (isolate Uganda/A7094A4/1948) Genome polyprotein (NS4A), recombinant protein. |
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Gag Polyprotein (gag) Antibody |
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| 20-abx317799 | Abbexa |
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Gag Polyprotein (gag) Antibody |
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| 20-abx318946 | Abbexa |
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Structural Polyprotein (VP2) Antibody |
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| abx224337-100ug | Abbexa | 100 ug | EUR 411 |
Gag Polyprotein (GAG) Antibody |
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| abx331332-100ul | Abbexa | 100 ul | EUR 425 |
Gag Polyprotein (GAG) Antibody (Biotin) |
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| 20-abx106336 | Abbexa |
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Gag Polyprotein (GAG) Antibody (FITC) |
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| 20-abx107749 | Abbexa |
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Gag Polyprotein (GAG) Antibody (HRP) |
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| 20-abx317800 | Abbexa |
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Gag Polyprotein (GAG) Antibody (FITC) |
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| 20-abx317801 | Abbexa |
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Gag Polyprotein (GAG) Antibody (Biotin) |
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| 20-abx317802 | Abbexa |
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Gag Polyprotein (GAG) Antibody (HRP) |
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| 20-abx318947 | Abbexa |
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Gag Polyprotein (GAG) Antibody (FITC) |
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| 20-abx318948 | Abbexa |
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Gag Polyprotein (GAG) Antibody (Biotin) |
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| 20-abx318949 | Abbexa |
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Non-Structural Polyprotein Porf1 (ORF1) Antibody |
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| 20-abx300971 | Abbexa |
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Recombinant CHIKV Structural Polyprotein |
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| VAng-Lsx0030-inquire | Creative Biolabs | inquire | Ask for price |
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Description: CHIKV Structural Polyprotein, recombinant protein from E. coli. |
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Turnip mosaic virus Polyprotein |
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| 1-CSB-EP2708TJM | Cusabio |
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Description: Recombinant Turnip mosaic virus Polyprotein,partial expressed in E.coli |
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Nonetheless, due to its extremely valued timber, H. hainanensis has suffered from overexploitation, resulting in a pointy inhabitants decline. To facilitate the conservation of this species, genetic range and inhabitants construction had been assessed utilizing 12 SSR markers for 10 populations sampled throughout Hainan Island. In comparison with non-threatened Hopea species, H. hainanensis exhibited decreased general genetic range and elevated inhabitants differentiation (AMOVA: FST = 0.23). Bayesian model-based clustering and principal coordinate evaluation constantly assigned H. hainanensis people into three genetic teams, which had been discovered to be widespread and overlapping geographically.
