Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans

Human-SARS-CoV-2 interactome and human genetic diversity: TMPRSS2-rs2070788, associated with severe influenza, and its population genetics caveats in Native Americans

For human/SARS-CoV-2 interactome genes ACE2, TMPRSS2 and BSG, there’s a convincing proof of affiliation in Asians with influenza-induced SARS for TMPRSS2-rs2070788, tag-SNP of the eQTL rs383510. This case illustrates the significance of inhabitants genetics and of sequencing knowledge within the design of genetic affiliation research in several human populations: the excessive linkage disequilibrium (LD) between rs2070788 and rs383510 is Asian-specific.
Leveraging on a mixture of genotyping and sequencing knowledge for Native Individuals (uncared for in genetic research), we present that whereas their frequencies of the Asian tag-SNP rs2070788 is, surprisingly, the best worldwide, it isn’t in LD with the eQTL rs383510, that subsequently, must be straight genotyped in genetic affiliation research of SARS in populations with Native American ancestry.

PRICKLE1 × FOCAD Interplay Revealed by Genome-Broad vQTL Evaluation of Human Facial Traits

The human face is a extremely advanced and variable construction ensuing from the intricate coordination of quite a few genetic and non-genetic elements. A whole bunch of genomic loci impacting quantitative facial options have been recognized.
Whereas these associations have been proven to affect morphology by altering the imply dimension and form of facial measures, their impact on trait variance stays unclear. We carried out a genome-wide affiliation evaluation for the variance of 20 quantitative facial measurements in 2,447 European people and recognized a number of suggestive variance quantitative trait loci (vQTLs).
These vQTLs guided us to conduct an environment friendly seek for gene-by-gene (G × G) interactions, which uncovered an interplay between PRICKLE1 and FOCAD affecting cranial base width. We replicated this G × G interplay sign on the locus stage in an extra 5,128 Korean people.
We used the hypomorphic Prickle1 Beetlejuice (Prickle1 Bj ) mouse line to straight take a look at the perform of Prickle1 on the cranial base and noticed wider cranial bases in Prickle1 Bj/Bj . Importantly, we noticed that the Prickle1 and Focadhesin proteins co-localize in murine cranial base chondrocytes, and this co-localization is irregular within the Prickle1 Bj/Bj mutants.
Taken collectively, our findings uncovered a novel G × G interplay impact in people with robust help from each epidemiological and molecular research. These outcomes spotlight the potential of finding out measures of phenotypic variability in gene mapping research of facial morphology.

Proof for opposing selective forces working on human-specific duplicated TCAF genes in Neanderthals and people

TRP channel-associated issue half (TCAF1/TCAF2) proteins antagonistically regulate the cold-sensor protein TRPM8 in a number of human tissues. Understanding their significance has been difficult given the locus spans a gap-ridden area with advanced segmental duplications in GRCh38. Utilizing long-read sequencing, we sequence-resolve the locus, annotate full-length TCAF fashions in primate genomes, and present substantial human-specific TCAF copy quantity variation.
We determine two human tremendous haplogroups, H4 and H5, and set up that TCAF duplications originated ~1.7 million years in the past however diversified solely in Homo sapiens by recurrent structural mutations. Conversely, in all archaic-hominin samples the fixation for a particular H4 haplotype with out duplication is probably going on account of constructive choice.
Right here, our outcomes of TCAF copy quantity enlargement, choice alerts in hominins, and differential TCAF2 expression between haplogroups and excessive TCAF2 and TRPM8 expression in liver and prostate in modern-day people suggest TCAF diversification amongst hominins doubtlessly in response to chilly or dietary diversifications.

A world map of associations between varieties of protein posttranslational modifications and human genetic ailments

There are >200 varieties of protein posttranslational modifications (PTMs) described in eukaryotes, every with distinctive proteome protection and capabilities. We hypothesized that some genetic ailments could also be attributable to the removing of a particular kind of PTMs by genomic variants and the resultant deregulation of explicit capabilities.
We collected >320,000 human PTMs representing 59 varieties and crossed them with >4M nonsynonymous DNA variants annotated with predicted pathogenicity and illness associations. We report >1.74M PTM-variant co-occurrences that an enrichment evaluation distributed into 215 pairwise associations between 18 PTM varieties and 148 genetic ailments.
Of them, 42% weren’t beforehand described. Elimination of lysine acetylation exerts probably the most pronounced impact, and fewer studied PTM varieties equivalent to S-glutathionylation or S-nitrosylation present relevance. Utilizing pathogenicity predictions, we recognized PTM websites that will produce explicit ailments if prevented. Our outcomes present proof of a considerable affect of PTM-specific removing on the pathogenesis of genetic ailments and phenotypes.

Human Codon Utilization: The Genetic Foundation of Pathogen Latency

Infectious ailments pose two important compelling points. First, the identification of the molecular elements that enable continual infections, that’s, the customarily fully asymptomatic coexistence of infectious brokers with the human host. Second, the definition of the mechanisms that enable the swap from pathogen dormancy to pathologic (re)activation.
Furthering earlier research, the current examine (1) analyzed the frequency of prevalence of synonymous codons in coding DNA, that’s, codon utilization, as a genetic device that guidelines protein expression; (2) described how human codon utilization can inhibit protein expression of infectious brokers throughout latency, in order that pathogen genes the codon utilization of which doesn’t conform to the human codon utilization can’t be translated; and (3) framed human codon utilization among the many front-line devices of the innate immunity towards infections.
In parallel, it was proven that, whereas genetics can account for the molecular foundation of pathogen latency, the modifications of the quantitative relationship between codon frequencies and isoaccepting tRNAs throughout cell proliferation supply a biochemical mechanism that explains the pathogen switching to (re)activation. Immunologically, this examine warns that utilizing codon optimization methodologies can (re)activate, potentiate, and immortalize in any other case quiescent, asymptomatic pathogens, thus resulting in uncontrollable pandemics.

Engineered human induced pluripotent cells allow genetic code enlargement in mind organoids

Human induced pluripotent stem cell (hiPSC) expertise has revolutionized human biology. A variety of cell varieties and tissue fashions will be derived from hiPSCs to review advanced human ailments. Right here, we use PiggyBac mediated transgenesis to engineer hiPSCs with an expanded genetic code. We reveal that genomic integration of expression cassettes for a pyrrolysyl-tRNA synthetase (PylRS), pyrrolysyl-tRNA (PylT) and the goal protein of curiosity permits site-specific incorporation of a non-canonical amino acid (ncAA) in response to amber cease codons.

West Nile Virus Envelope Antibody

24284-100ul 100ul
EUR 468

West Nile Virus Envelope Antibody

3437-002mg 0.02 mg
EUR 206.18
Description: West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Envelope Antibody

3437-01mg 0.1 mg
EUR 523.7
Description: West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Envelope Antibody

3439-002mg 0.02 mg
EUR 206.18
Description: West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Envelope Antibody

3439-01mg 0.1 mg
EUR 523.7
Description: West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Envelope Antibody

3441-002mg 0.02 mg
EUR 206.18
Description: West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Envelope Antibody

3441-01mg 0.1 mg
EUR 523.7
Description: West Nile Virus Envelope Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. While the viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway, the highly glycosylated envelope protein plays a major role for WNV entry into target cells as this entry can be inhibited by using a recombinant domain III from the envelope glycoprotein. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Envelope Virus Protein

20-abx260322
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

West Nile Virus Envelope Protein Antibody

abx022312-1mg 1 mg
EUR 1296

West Nile Virus Envelope Protein Antibody

abx022314-1mg 1 mg
EUR 1228.8

West Nile Virus Envelope Protein Antibody

abx022315-1mg 1 mg
EUR 1296

West Nile Virus Envelope Protein Antibody

abx022316-1mg 1 mg
EUR 1296

Recombinant West Nile Envelope Virus

7-07960 100µg Ask for price

Recombinant West Nile Envelope Virus

7-07961 500µg Ask for price

Recombinant West Nile Envelope Virus

7-07962 1000µg Ask for price

West Nile Envelope Virus (Recombinant)

22060756-1 100 µg
EUR 264.47

Polyclonal West Nile Virus Envelope Antibody

APR11226G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human West Nile Virus Envelope . This antibody is tested and proven to work in the following applications:

Polyclonal West Nile Virus Envelope Antibody

AMM05448G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human West Nile Virus Envelope . This antibody is tested and proven to work in the following applications:

Polyclonal West Nile Virus Envelope Antibody

AMM05449G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human West Nile Virus Envelope . This antibody is tested and proven to work in the following applications:

West Nile Virus Envelope recombinant antigen

00401-V-01mg 0,1 mg
EUR 321
Description: West Nile Virus Envelope recombinant antigen-Immunodominant region

West Nile Virus Envelope recombinant antigen

00401-V-1000ug 1000 ug
EUR 1539
Description: West Nile Virus Envelope recombinant antigen-Immunodominant region

West Nile Virus Envelope recombinant antigen

8822 100 ug
EUR 529.8
Description: This is West Nile Virus Envelope recombinant antigen for ELISA,WB.

West Nile Virus Envelope Recombinant Protein

53-361 0.01 mg
EUR 714.3
Description: West Nile Virus Envelope Recombinant Protein

Recombinant West Nile Virus Envelope Protein

P1065-10 each
EUR 189.6

Recombinant West Nile Virus Envelope Protein

P1065-50 each
EUR 366

West Nile Virus Envelope Protein ELISA Kit

VPK-5154 96 assays
EUR 660

Mouse antibody for West Nile Virus Envelope

3655 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against West Nile Virus Envelope for WB, ELISA.

Mouse antibody for West Nile Virus Envelope

3661 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against West Nile Virus Envelope for WB, ELISA.

Mouse antibody for West Nile Virus Envelope

3671 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against West Nile Virus Envelope for WB, ELISA.

OPNB00039-100UG - West Nile Virus - Envelope protein

OPNB00039-100UG 100ug
EUR 658

OPNB00039-500UG - West Nile Virus - Envelope protein

OPNB00039-500UG 500ug
EUR 2656

West Nile Virus EnvelopeHis

PR-1275 100µg
EUR 300.7
Description: recombinant, E. coli

OAGA07998-100UL - West Nile virus Envelope protein Antibody

OAGA07998-100UL 100ul
EUR 369

OAGA08675-100UL - West Nile virus Envelope protein Antibody

OAGA08675-100UL 100ul
EUR 369

West Nile Virus Envelope Recombinant Protein 6-his liquid

IWNVWNVENVR6HIS10UG each
EUR 851
Description: West Nile Virus Envelope Recombinant Protein 6-his liquid

West Nile Virus Envelope recombinant antigen-Immunodominant region

00401-V 1 MG
EUR 850

West Nile Virus Envelope recombinant antigen-Immunodominant region

00401-V-100ugvial 100 ug/vial
EUR 150
Description: West Nile Virus Envelope recombinant antigen-Immunodominant region

Recombinant West Nile Virus Envelope Protein (N-terminus), His-tagged

DAG566 100ug
EUR 786

Recombinant West Nile Virus WNV Envelope Protein, His, E.coli-1mg

QP13964-1mg 1mg
EUR 1513.2

Recombinant West Nile Virus WNV Envelope Protein, His, E.coli-100ug

QP13964-100ug 100ug
EUR 261.6

Recombinant West Nile Virus WNV Envelope Protein, His, E.coli-500ug

QP13964-500ug 500ug
EUR 795.6

West Nile Virus Envelope full length recombinant antigen 42 kDa region

00403-V 1 MG
EUR 850

West Nile Virus Envelope full length recombinant antigen 42 kDa region

00403-V-100ugvial 100 ug/vial
EUR 150
Description: West Nile Virus Envelope full length recombinant antigen 42 kDa region

West Nile Virus Envelope Protein mouse monoclonal antibody, clone B857M, Purified

AM31657PU-N 1 mg Ask for price

West Nile Virus Envelope Protein mouse monoclonal antibody, clone B851M, Purified

AM31658PU-N 1 mg Ask for price

West Nile Virus Envelope Protein mouse monoclonal antibody, clone B849M, Purified

AM31659PU-N 1 mg Ask for price

West Nile Virus Envelope Protein mouse monoclonal antibody, clone B847M, Purified

AM31661PU-N 1 mg Ask for price

Rabbit Polyclonal Anti-West Nile Virus Envelope Antibody

TA160067 100 µg Ask for price

Rabbit Polyclonal Anti-West Nile Virus Envelope Antibody

TA160068 100 µg Ask for price

Rabbit Polyclonal Anti-West Nile Virus Envelope Antibody

TA160069 100 µg Ask for price

Rabbit Anti-West Nile Virus Envelope Protein Antibody (9E2)

MAB12297-100 0.1
EUR 825.42
Description: Rabbit polyclonal antibody specific for West Nile virus Envelope (clone 9E2)

Rabbit Anti-West Nile Virus Envelope Protein Antibody (9E2)

MAB12297-200 0.2
EUR 1224.72
Description: Rabbit polyclonal antibody specific for West Nile virus Envelope (clone 9E2)

Recombinant (E. coli) West Nile N-terminus Envelope Virus (WNV) (E. Coli, >95%, 42 Kda, his-tag)

RP-1456 50 ug
EUR 343.2

Recombinant (E. coli) West Nile Virus Envelop (WNV-E) protein (>95%, ~42 Kda, His-tag)

WNVE15-R-50 50 ug
EUR 343.2

Recombinant (HEK) West Nile Virus Envelop (WNV-E, domain III) protein (>95%, ~12 Kda, His-tag)

WNVE16-R-50 50 ug
EUR 489.6

Rabbit Anti-West Nile Virus (WNV) envelop protein antiserum

WNV16-S 100 ul
EUR 548.4

Recombinant (yeast) West Nile Virus Envelop (WNV-E, domain III, lineage 2) protein (>95%, ~12 Kda, His-tag)

WNVE17-R-50 50 ug
EUR 489.6

West nile virus

Oneq-VH054-OneqVH054100R Oneq-VH054-100R
EUR 1028

West nile virus

Oneq-VH054-OneqVH054150R Oneq-VH054-150R
EUR 1438

West nile virus

Oneq-VH054-OneqVH05450R Oneq-VH054-50R
EUR 728

West nile virus

PCR-VH054-PCRVH05448R PCR-VH054-48R
EUR 485

West nile virus

PCR-VH054-PCRVH05496R PCR-VH054-96R
EUR 685

West Nile virus lysate

NAT41561-100 0.1
EUR 512.85
Description: Purified West Nile virus Lysate (NY 2001-6263 strain).

West Nile virus antibody

10-1436 100 ug
EUR 489.6
Description: Mouse monoclonal West Nile virus antibody

West Nile virus antibody

10-1437 100 ug
EUR 489.6
Description: Mouse monoclonal West Nile virus antibody

West Nile Virus ENV recombinant antigen

00403-V-01mg 0,1 mg
EUR 321
Description: West Nile Virus Envelope full length recombinant antigen 42 kDa region

West Nile Virus ENV recombinant antigen

00403-V-1000ug 1000 ug
EUR 1539
Description: West Nile Virus Envelope full length recombinant antigen 42 kDa region

Virus West Nile Virus (WNV) Protein

abx670276-100ug 100 ug
EUR 794.4

Mouse Anti-West Nile Virus Envelop Protein (WNV-E) IgG ELISA kit, 96 tests, Quantitative

910-280-WNG 1 Kit
EUR 1000.8

Mouse Anti-West Nile Virus Envelop Protein (WNV-E) IgM ELISA kit, 96 tests, Quantitative

910-285-WNM 1 Kit
EUR 1000.8

Human Anti-West Nile Virus Envelop Protein (WNV-E) IgG ELISA kit, 96 tests, Quantitative

910-380-WNG 1 Kit
EUR 1000.8

Human Anti-West Nile Virus Envelop Protein (WNV-E) IgM ELISA kit, 96 tests, Quantitative

910-385-WNM 1 Kit
EUR 1000.8

Monkey Anti-West Nile Virus Envelop Protein (WNV-E) IgG ELISA kit, 96 tests, Quantitative

910-480-WNG 1 Kit
EUR 1000.8

Monkey Anti-West Nile Virus Envelop Protein (WNV-E) IgM ELISA kit, 96 tests, Quantitative

910-485-WNM 1 Kit
EUR 1000.8

West nile virus PCR kit

PCR-VH054-48R 50T
EUR 987.6

West nile virus PCR kit

PCR-VH054-96R 100T
EUR 1335.6

West Nile Virus Pre-MHis

PR-1274 100µg
EUR 300.7
Description: recombinant, E. coli

West Nile Virus NS1 protein

80-1546 100 ug
EUR 541.2
Description: Purified Recombinant West Nile Virus NS1 protein (His tag)

West Nile Virus NS1 Protein

WNV-NS1-100 0.1
EUR 318.94
Description: Recombinant West Nile Virus NS1 protein produced in 293 human cells. Protein contains a C-terminal His-tag.

West Nile Virus NS1 Protein

WNV-NS1-500 0.5
EUR 1305.1
Description: Recombinant West Nile Virus NS1 protein produced in 293 human cells. Protein contains a C-terminal His-tag.

West Nile Virus (WNV) Antibody

abx412023-01mg 0.1 mg
EUR 610.8

West Nile Virus Core Peptide

3435P 0.05 mg
EUR 197.7
Description: (CT) West Nile Virus Core peptide

West Nile Virus Core Antibody

24281-100ul 100ul
EUR 468

West Nile virus protein (Horse)

30-1261 250 ug
EUR 548.4
Description: Purified recombinant West Nile virus protein (Horse)

West Nile Virus Core Antibody

3435-002mg 0.02 mg
EUR 206.18
Description: West Nile Virus Core Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.

West Nile Virus Core Antibody

3435-01mg 0.1 mg
EUR 523.7
Description: West Nile Virus Core Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.

West Nile Virus Matrix Peptide

3429P 0.05 mg
EUR 197.7
Description: (IN) West Nile Virus Matrix peptide

West Nile Virus Matrix Peptide

3431P 0.05 mg
EUR 197.7
Description: (CT) West Nile Virus Matrix peptide

Native West Nile Virus antigen

DAGA-3052 1mg
EUR 1279.2

Native West Nile Virus antigen

DAGA-3053 1mg
EUR 1279.2

West Nile Virus Matrix Antibody

24278-100ul 100ul
EUR 468

West Nile Virus Matrix Antibody

24279-100ul 100ul
EUR 468

West Nile Virus Matrix Antibody

3429-002mg 0.02 mg
EUR 206.18
Description: West Nile Virus Matrix Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Matrix Antibody

3429-01mg 0.1 mg
EUR 523.7
Description: West Nile Virus Matrix Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Matrix Antibody

3431-002mg 0.02 mg
EUR 206.18
Description: West Nile Virus Matrix Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin.

West Nile Virus Matrix Antibody

3431-01mg 0.1 mg
EUR 523.7
Description: West Nile Virus Matrix Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins. However, when the viruses are inside of infected cells, the matrix protein exists in its "pre-M" form as a heterodimer with the envelope proteins. Cleavage of the "pre-M" protein to its mature form occurs during release of the virus; this cleavage leas to the dissociation of the heterodimers. The WNV receptor has recently been identified as alpha v beta 3 integrin.

Recombinant West Nile virus protein

0557-001 100 ug
EUR 435

West nile virus RT PCR kit

RTq-VH054-100R 100T
EUR 1573.2

West nile virus RT PCR kit

RTq-VH054-150R 150T
EUR 2144.4

West nile virus RT PCR kit

RTq-VH054-50R 50T
EUR 1155.6

Monoclonal anti-West Nile Virus (WNV) envelop protein IgG (non-reactive with Dengue, SLE, JEV)

WNV11-M 100 ul
EUR 578.4

Monoclonal anti-West Nile Virus (WNV) envelop protein IgG #2 (crossreacts with Dengues, SLE, JEV)

WNV12-M 100 ul
EUR 578.4

QPCR Kit RNA West Nile virus

MOL6366 EACH
EUR 997.2

West Nile Virus Pre-M Protein

abx060681-100ug 100 ug
EUR 794.4

Zika virus envelope protein

30-1932 100 ug
EUR 457.2
Description: Recombinant Zika virus envelope protein

Zika virus envelope protein

30-1935 100 ug
EUR 289.2
Description: Recombinant Zika virus envelope protein

Zika Virus Envelope Protein

abx061381-1mg 1 mg
EUR 1722

Zika Virus Envelope Protein

abx160022-1mg 1 mg
EUR 1746

Zika virus envelope antibody

10-2712 1 mg
EUR 678
Description: Mouse monoclonal Zika virus envelope antibody

Zika virus envelope antibody

10-2713 1 mg
EUR 678
Description: Mouse monoclonal Zika virus envelope antibody

Zika virus envelope antibody

10-2714 1 mg
EUR 678
Description: Mouse monoclonal Zika virus envelope antibody

Zika virus envelope antibody

10-2715 1 mg
EUR 678
Description: Mouse monoclonal Zika virus envelope antibody

Zika Virus Envelope Antibody

abx024128-1mg 1 mg
EUR 1730.4

Zika Virus Envelope Antibody

abx024129-1mg 1 mg
EUR 1730.4

Zika Virus Envelope Antibody

abx024130-1mg 1 mg
EUR 1730.4

Zika Virus Envelope Antibody

abx024131-1mg 1 mg
EUR 1730.4

Zika Virus Envelope Antibody

abx024132-1mg 1 mg
EUR 1696.8

Zika Virus Envelope Antibody

abx024133-1mg 1 mg
EUR 1696.8

West Nile Virus Core Protein Antibody

abx023202-100ug 100 ug
EUR 811.2

OPNB00058-100UG - West Nile Virus -NS1

OPNB00058-100UG 100ug
EUR 401

OPNB00058-500UG - West Nile Virus -NS1

OPNB00058-500UG 500ug
EUR 1709

OPEF01486-1MG - West Nile Virus Antigen

OPEF01486-1MG 1mg
EUR 589

OPEF01487-1MG - West Nile Virus Antigen

OPEF01487-1MG 1mg
EUR 589

Polyclonal West Nile Virus Core Antibody

AMM05447G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human West Nile Virus Core . This antibody is tested and proven to work in the following applications:

OAMA02321-1MG - West Nile Virus Antibody

OAMA02321-1MG 1mg
EUR 899

OAMA02438-1MG - West Nile Virus Antibody

OAMA02438-1MG 1mg
EUR 899

OAMA02469-1MG - West Nile Virus Antibody

OAMA02469-1MG 1mg
EUR 899

OAMA02481-1MG - West Nile Virus Antibody

OAMA02481-1MG 1mg
EUR 949

OPMA04763-100UG - West Nile Virus Protein

OPMA04763-100UG 0.1MG
EUR 559

Humanized Monoclonal Anti-Flavivirus Envelope Protein DII (EDII) IgG1 (Crossreactive with Dengue, Zika, West Nile, JEV, etc)

ZENV17-M 100 ul
EUR 578.4

Polyclonal West Nile Virus Matrix Antibody

APR11227G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human West Nile Virus Matrix . This antibody is tested and proven to work in the following applications:

Polyclonal West Nile Virus Matrix Antibody

AMM05450G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human West Nile Virus Matrix . This antibody is tested and proven to work in the following applications:

West Nile Virus E protein (His tag)

80-1339 100 ug
EUR 289.2
Description: Purified recombinant West Nile Virus E protein (His tag)
Neural stem cells, neurons and mind organoids derived from the engineered hiPSCs proceed to precise the amber suppression equipment and produce ncAA-bearing reporter. The integrated ncAA can function a minimal bioorthogonal deal with for additional modifications by labeling with fluorescent dyes. Website-directed ncAA mutagenesis will open a variety of functions to probe and manipulate proteins in mind organoids and different hiPSC-derived cell varieties and complicated tissue fashions.

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