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Title- Genomic landscape of squamous cell carcinoma- Different genetic pathways culminating in a common phenotype
Introduction: Squamous cell carcinomas (SqCCs) are the commonest stable tumors in people and are discovered throughout a number of organ programs. Though, built-in evaluation of genetic alterations expose similarities between SqCCs from varied physique websites, sure genes seem like extra regularly mutated in a given SqCC. These delicate variations could maintain the important thing to figuring out the differentiation traits and predicting aggressiveness of tumors.
Supplies and technique: Fifty-four instances of SqCCs, during which the first location of the tumor may very well be ascertained by medical and radiological findings, have been included on this research. Subsequent era sequencing knowledge was analyzed for recurrent genetic abnormalities.
Outcomes: Genetic alterations have been present in 219 genes within the 54 instances studied. TP53 mutations have been discovered to be extra frequent in pulmonary SqCCs (86.5%) as in comparison with non-pulmonary SqCCs (58.8%) (p<0.05). NOTCH gene household mutations and CREBBP mutations have been restricted to non-pulmonary SqCC (p<0.005) and have been mutated in 41.2% and 17.6% instances.
Conclusion: An in depth comparative evaluation of the genetic alterations recognized by sequencing recognized larger frequency of TP53 mutations in lung SqCCs as in comparison with non-pulmonary SqCCs. NOTCH and CREBPP mutations have been discovered to be absent in lung and head and neck SqCCs and extra frequent in SqCCs from different areas
The genetic foundation for the evolution of soma: mechanistic proof for the co-option of a stress-induced gene right into a developmental grasp regulator
In multicellular organisms with specialised cells, essentially the most important distinction amongst cell sorts is between reproductive (germ) cells and non-reproductive/somatic cells (soma). Though soma contributed to the marked enhance in complexity of many multicellular lineages, little is understood about its evolutionary origins. We’ve beforehand instructed that the evolution of genes answerable for the differentiation of somatic cells concerned the co-option of life historical past trade-off genes that in unicellular organisms enhanced survival at a price to speedy copy. Within the multicellular inexperienced alga, Volvox carteri, cell destiny is established early in growth by the differential expression of a grasp regulatory gene often known as regA.
A carefully associated RegA-Like Sequence (RLS1) is current in its single-celled relative, Chlamydomonas reinhardtii. RLS1 is expressed in response to emphasize, and we proposed that an environmentally induced RLS1-like gene was co-opted right into a developmental pathway within the lineage resulting in V. carteri. Nonetheless, the precise evolutionary situation answerable for the postulated co-option occasion stays to be decided. Right here, we present that along with being developmentally regulated, regA will also be induced by environmental cues, indicating that regA has maintained its ancestral regulation.
We additionally discovered that the absence of a practical RegA protein confers elevated sensitivity to emphasize, in keeping with RegA having a direct or oblique function in stress responses. Total, this research (i) supplies mechanistic proof for the co-option of an environmentally induced gene into a serious developmental regulator, (ii) helps the view that main morphological improvements can evolve through regulatory modifications and (iii) argues for the function of stress within the evolution of multicellular complexity.
Chromosome-level de novo meeting of Coprinopsis cinerea A43mut B43mut pab1-1 #326 and genetic variant identification of mutants utilizing Nanopore MinION sequencing
The homokaryotic Coprinopsis cinerea pressure A43mut B43mut pab1-1 #326 is a extensively used experimental mannequin for developmental research in mushroom-forming fungi. It may possibly develop on outlined synthetic media and full the entire lifecycle inside two weeks. The mutations in mating sort components A and B end result within the particular function of clamp formation and fruiting with out mating. This function permits investigations and manipulations with a homokaryotic genetic background. Present genome meeting of pressure #326 was based mostly on short-read sequencing knowledge and was extremely fragmented, resulting in the bias in gene annotation and downstream analyses.
Right here, we report a chromosome-level genome meeting of pressure #326. Oxford Nanopore Expertise (ONT) MinION sequencing was used to get lengthy reads. Illumina brief reads was used to shine the sequences. A mixed meeting yield 13 chromosomes and a mitochondrial genome as particular person scaffolds. The meeting has 15,250 annotated genes with a excessive synteny with the C. cinerea pressure Okayama-7 #130. This meeting has nice enchancment on contiguity and annotations. It’s a appropriate reference for additional genomic research, particularly for the genetic, genomic and transcriptomic analyses in ONT lengthy reads. Single nucleotide variants and structural variants in six mutagenized and cisplatin-screened mutants may very well be recognized and validated. A 66 bp deletion in Ras GTPase-activating protein (RasGAP) was present in all mutants.
Recombinant Hepatitis C virus Genome polyprotein |
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| MBS7037961-5x01mg | MyBiosource | 5x0.1mg | EUR 11785 |
Recombinant Hepatitis C virus Genome polyprotein |
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| MBS7037962-002mg | MyBiosource | 0.02mg | EUR 1400 |
Recombinant Hepatitis C virus Genome polyprotein |
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| MBS7037962-01mg | MyBiosource | 0.1mg | EUR 2365 |
Recombinant Hepatitis C virus Genome polyprotein |
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| MBS7037962-5x01mg | MyBiosource | 5x0.1mg | EUR 10600 |
Hepatitis C virus genotype 1a Genome polyprotein |
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| 1-CSB-EP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in E.coli |
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Hepatitis C virus genotype 1a Genome polyprotein |
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| 1-CSB-MP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in Mammalian cell |
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Hepatitis C virus genotype 1b Genome polyprotein |
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| 1-CSB-YP530838HVQ(A3) | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial expressed in Yeast |
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Hepatitis C virus genotype 1b Genome polyprotein |
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| 1-CSB-YP530838HVQ(A4) | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial expressed in Yeast |
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Recombinant Human hepatitis A virus genotype IA Genome polyprotein |
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| MBS1163442-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 1130 |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein |
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| MBS1163442-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 875 |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein |
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| MBS1163442-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 1010 |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein |
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| MBS1163442-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 1130 |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein |
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| MBS1163442-05mgEColi | MyBiosource | 0.5mg(E-Coli) | EUR 1245 |
Recombinant Hepatitis C virus Genome polyprotein,partial |
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| AP72393 | SAB | each | Ask for price |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1197403-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1200 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1197403-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 1710 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1018847-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1200 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1018847-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 1710 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1017822-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1200 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1017822-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 1710 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1087197-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1200 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1087197-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 1710 |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS1041882-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS7060967-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS7083727-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS7060004-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus Genome polyprotein, partial |
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| MBS7060367-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IIA Genome polyprotein |
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| MBS1279215-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Simian hepatitis A virus genotype V Genome polyprotein |
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| MBS1013869-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Simian hepatitis A virus genotype VI Genome polyprotein |
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| MBS1044911-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 870 |
Recombinant Simian hepatitis A virus genotype VI Genome polyprotein |
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| MBS1044911-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 480 |
Recombinant Simian hepatitis A virus genotype VI Genome polyprotein |
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| MBS1044911-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 700 |
Recombinant Simian hepatitis A virus genotype VI Genome polyprotein |
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| MBS1044911-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 625 |
Recombinant Simian hepatitis A virus genotype VI Genome polyprotein |
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| MBS1044911-05mgEColi | MyBiosource | 0.5mg(E-Coli) | EUR 690 |
Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein |
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| MBS1431010-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 1080 |
Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein |
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| MBS1431010-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 755 |
Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein |
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| MBS1431010-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 915 |
Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein |
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| MBS1431010-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 1010 |
Recombinant Human hepatitis A virus genotype IIIA Genome polyprotein |
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| MBS1431010-05mgEColi | MyBiosource | 0.5mg(E-Coli) | EUR 1110 |
Recombinant Hepatitis C virus genotype 4a Genome polyprotein |
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| MBS1079380-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1085 |
Recombinant Hepatitis C virus genotype 4a Genome polyprotein |
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| MBS1079380-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 675 |
Recombinant Hepatitis C virus genotype 4a Genome polyprotein |
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| MBS1079380-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 840 |
Recombinant Hepatitis C virus genotype 4a Genome polyprotein |
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| MBS1079380-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 790 |
Recombinant Hepatitis C virus genotype 4a Genome polyprotein |
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| MBS1079380-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 980 |
Recombinant Hepatitis GB virus B Genome polyprotein, partial |
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| MBS7085832-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IB Genome polyprotein, partial |
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| MBS1220473-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein, partial |
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| MBS1207515-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IIB Genome polyprotein, partial |
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| MBS1307563-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein, partial |
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| MBS1255162-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein, partial |
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| MBS1251717-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Simian hepatitis A virus genotype IV Genome polyprotein, partial |
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| MBS1031233-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IB Genome polyprotein, partial |
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| MBS1057291-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IA Genome polyprotein, partial |
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| MBS1479676-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Human hepatitis A virus genotype IIIB Genome polyprotein, partial |
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| MBS1010551-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| CSB-EP333180HFD | Cusabio | 3004 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| CSB-EP333180HFD-20ug | Cusabio | 20ug | Ask for price |
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Description: 192-325aa |
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Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| CSB-MP333180HFD | Cusabio | 4998 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| CSB-MP333180HFD-20ug | Cusabio | 20ug | Ask for price |
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Description: 192-325aa |
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Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial |
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| AP73727 | SAB | each | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial |
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| AP73728 | SAB | each | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| CSB-YP530838HVQ(A3) | Cusabio | 6465 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| CSB-YP530838HVQ(A3)-20ug | Cusabio | 20ug | Ask for price |
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Description: 2-177aa |
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Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| CSB-YP530838HVQ(A4) | Cusabio | 6466 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| CSB-YP530838HVQ(A4)-20ug | Cusabio | 20ug | Ask for price |
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Description: 192-358aa |
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Recombinant Hepatitis C virus genotype 6b Genome polyprotein, partial |
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| MBS1161053-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 6b Genome polyprotein, partial |
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| MBS1161053-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1169939-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1169939-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 6d Genome polyprotein, partial |
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| MBS1226183-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 6d Genome polyprotein, partial |
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| MBS1226183-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1238854-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1238854-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 6h Genome polyprotein, partial |
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| MBS1239793-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 6h Genome polyprotein, partial |
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| MBS1239793-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 2a Genome polyprotein, partial |
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| MBS1185658-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 2a Genome polyprotein, partial |
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| MBS1185658-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1134475-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1261568-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1261568-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 6a Genome polyprotein, partial |
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| MBS1111818-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 6a Genome polyprotein, partial |
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| MBS1111818-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 5a Genome polyprotein, partial |
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| MBS1027168-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 5a Genome polyprotein, partial |
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| MBS1027168-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1004937-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1004937-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1005431-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 375 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1005431-002mgMammalianCell | MyBiosource | 0.02mg(Mammalian-Cell) | EUR 425 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1005431-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 635 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1005431-01mgMammalianCell | MyBiosource | 0.1mg(Mammalian-Cell) | EUR 1015 |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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| MBS1005431-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1925 |
Recombinant Hepatitis C virus genotype 5a Genome polyprotein, partial |
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| MBS1001699-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 5a Genome polyprotein, partial |
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| MBS1001699-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 6k Genome polyprotein, partial |
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| MBS1072352-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 6k Genome polyprotein, partial |
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| MBS1072352-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 2b Genome polyprotein, partial |
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| MBS1066487-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 2b Genome polyprotein, partial |
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| MBS1066487-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1081858-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 2505 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS1081858-1mgYeast | MyBiosource | 1mg(Yeast) | EUR 2980 |
Recombinant Hepatitis C virus genotype 2c Genome polyprotein, partial |
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| MBS7085011-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 6a Genome polyprotein, partial |
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| MBS7081854-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1c Genome polyprotein, partial |
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| MBS7090883-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 3b Genome polyprotein, partial |
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| MBS7091092-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 3a Genome polyprotein, partial |
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| MBS7091930-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 3a Genome polyprotein, partial |
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| MBS7091931-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 6g Genome polyprotein, partial |
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| MBS7085811-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 3k Genome polyprotein, partial |
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| MBS7086666-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS7097404-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 2a Genome polyprotein, partial |
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| MBS7097910-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 2k Genome polyprotein, partial |
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| MBS7099413-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 2b Genome polyprotein, partial |
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| MBS7099644-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1c Genome polyprotein, partial |
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| MBS7094099-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS7102489-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423307-002mg | MyBiosource | 0.02mg | EUR 505 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423307-01mg | MyBiosource | 0.1mg | EUR 895 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423307-05mg | MyBiosource | 0.5mg | EUR 1975 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423307-5x05mg | MyBiosource | 5x0.5mg | EUR 8735 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423308-002mg | MyBiosource | 0.02mg | EUR 505 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423308-01mg | MyBiosource | 0.1mg | EUR 895 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423308-05mg | MyBiosource | 0.5mg | EUR 1975 |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein, partial |
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| MBS9423308-5x05mg | MyBiosource | 5x0.5mg | EUR 8735 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) (HCV) Genome polyprotein |
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| MBS9420854-002mg | MyBiosource | 0.02mg | EUR 460 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) (HCV) Genome polyprotein |
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| MBS9420854-01mg | MyBiosource | 0.1mg | EUR 795 |
To make a greater use of ONT sequencing platform, we modified a high-molecular-weight genomic DNA isolation protocol based mostly on magnetic beads for filamentous fungi. This research confirmed using MinION to assemble a fungal reference genome and to carry out downstream research in a person laboratory. An experimental workflow was proposed, from DNA isolation and complete genome sequencing, to genome meeting and variant calling. Our outcomes offered options and parameters for fungal genomic evaluation on MinION sequencing platform.
