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Sex-dependent gene co-expression in the human body
Many pathophysiological mechanisms in human well being and illness are depending on intercourse. Methods biology approaches are efficiently used to decipher human illness etiology, but the impact of intercourse on gene community biology is generally unknown.
To deal with this, we used RNA-sequencing knowledge of over 700 people spanning 24 tissues from the Genotype-Tissue Expression challenge to generate a whole-body gene co-expression map and quantified the intercourse variations per tissue.
We discovered that of the 13,787 genes analyzed in 24 tissues, 29.5% of the gene co-expression is influenced by intercourse. For instance, skeletal muscle was predominantly enriched with genes co-expressed stronger in males, whereas thyroid primarily contained genes co-expressed stronger in females. This was accompanied by constant sex variations in pathway enrichment, together with hypoxia, epithelial-to-mesenchymal transition, and irritation over the human physique.
Moreover, multi-organ analyses revealed constant sex-dependent gene co-expression over quite a few tissues which was accompanied by enrichment of transcription issue binding motifs within the promoters of those genes.
Lastly, we present that many sex-biased genes are related to sex-biased illnesses, similar to autoimmunity and most cancers, and extra usually the goal of FDA-approved medication than non-sexbiased genes. Our examine means that intercourse impacts organic gene networks by variations in gene co-expression and that spotlight to the impact of intercourse on organic responses to medical medication is warranted.
Structural variants are a serious supply of gene expression variations in people and infrequently have an effect on a number of close by genes
Structural variants (SVs) are an necessary supply of human genome range however their practical results should not properly understood. We mapped 61,668 SVs in 613 people with deep genome sequencing knowledge from the GTEx challenge and measured their results on gene expression. We estimate that widespread SVs are causal at 2.66% of eQTLs, which is a 10.5-fold enrichment relative to their abundance within the genome and in line with prior work utilizing smaller pattern sizes.
Duplications and deletions have been probably the most impactful variant sorts, whereas the contribution of cell ingredient insertions was small (0.12% of eQTLs, 1.9-fold enriched). Multi-tissue evaluation of expression results revealed that gene-altering SVs present considerably extra constitutive results than different variant sorts, with 62.09% of coding SV-eQTLs energetic in all tissues with identified eQTL exercise in comparison with 23.08% of coding SNV- and indel-eQTLs, whereas noncoding SVs, SNVs and indels present broadly comparable patterns.
We additionally recognized 539 uncommon SVs related to close by gene expression outliers. Of those, 62.34% are noncoding SVs that present sturdy results on gene expression but modest enrichment at identified regulatory components, demonstrating that uncommon noncoding SVs are a serious supply of gene expression variations however stay troublesome to foretell from present annotations.
Each widespread and uncommon noncoding SVs usually present sturdy regional results on the expression of a number of genes: SV-eQTLs have an effect on a median of 1.82 close by genes in comparison with 1.09 genes affected by SNV- and indel-eQTLs, and 21.34% of uncommon expression-altering SVs present sturdy results on 2-9 completely different genes. We additionally observe important results on uncommon gene expression changes extending 1 Mb from the SV. This offers a mechanism by which particular person noncoding SVs could have sturdy or pleiotropic results on phenotypic variation and illness.
Technology of ‘designer erythroblasts’ missing a number of blood group programs from CRISPR/Cas9 gene-edited human-induced pluripotent stem cells
Regardless of the current developments in transfusion drugs, crimson blood cell (RBC) alloimmunization stays a problem for multiparous ladies and chronically transfused sufferers. At instances, diagnostic laboratories depend upon difficult-to-procure uncommon reagent RBCs for the identification of various alloantibodies in such topics.
We’ve got addressed this difficulty by creating erythroblasts with customized phenotypes (Rh null, GPB null and Kx null/Kell low) utilizing CRISPR/Cas9 gene-editing of a human induced pluripotent stem cell (hiPSC) father or mother line (OT1-1) for the blood group system genes: RHAG, GYPB and XK. Information RNAs have been cloned into Cas9-puromycin expression vector and transfected into OT1-1.
Genotyping was carried out to pick puromycin-resistant hiPSC KOs. CRISPR/Cas9 gene-editing resulted within the profitable technology of three KO strains, RHAG KO, GYPB KO and XK KO. The OT1-1 cell line, in addition to the three KO hiPSC strains, have been differentiated into CD34+ CD41+ CD235ab+ hematopoietic progenitor cells (HPCs) and subsequently to erythroblasts.
Native OT1-1 erythroblasts have been optimistic for the expression of Rh, MNS, Kell and H blood group programs. Differentiation of RHAG KO, GYPB KO and XK KO resulted within the formation of Rh null, GPB null and Kx null/Kell low erythroblasts, respectively. OT1-1 in addition to the three KO erythroblasts remained optimistic for RBC markers-CD71 and BAND3.
Erythroblasts have been principally on the polychromatic/ orthochromatic stage of differentiation. As much as ~400-fold enhance in erythroblasts derived from HPCs was noticed. The provision of customized erythroblasts generated from CRISPR/Cas9 gene-edited hiPSC needs to be a helpful addition to the instruments at present used for the detection of clinically necessary crimson cell alloantibodies.
Genomic Stability and Genetic Protection Methods in Dolosigranulum pigrum, a Candidate Useful Bacterium from the Human Microbiome
Dolosigranulum pigrum is positively related to indicators of well being in a number of epidemiological research of human nasal microbiota. Data of the essential biology of D. pigrum is a prerequisite for evaluating its potential for future therapeutic use; nevertheless, such knowledge are very restricted. To realize perception into D. pigrum‘s chromosomal construction, pangenome, and genomic stability, we in contrast the genomes of 28 D. pigrum strains that have been collected throughout 20 years.
Phylogenomic evaluation confirmed carefully associated strains circulating over this era and closure of 19 genomes revealed extremely conserved chromosomal synteny. Gene clusters concerned within the mobilome and in protection towards cell genetic components (MGEs) have been enriched within the accent genome versus the core genome.
A scientific evaluation for MGEs recognized the primary candidate D. pigrum prophage and insertion sequence. A scientific evaluation for genetic components that restrict the unfold of MGEs, together with restriction modification (RM), CRISPR-Cas, and deity-named protection programs, revealed strain-level range in host protection programs that localized to particular genomic websites, together with one RM system scorching spot. Evaluation of CRISPR spacers pointed to a wealth of MGEs towards which D. pigrum defends itself.
These outcomes reveal a task for horizontal gene switch and cell genetic components in pressure diversification whereas highlighting that in D. pigrum this happens inside the context of a extremely secure chromosomal group protected by quite a lot of protection mechanisms. IMPORTANCE Dolosigranulum pigrum is a candidate helpful bacterium with potential for future therapeutic use. That is based mostly on its optimistic associations with traits of well being in a number of research of human nasal microbiota throughout the span of human life.
For instance, excessive ranges of D. pigrum nasal colonization in adults predicts the absence of Staphylococcus aureus nasal colonization. Additionally, D. pigrum nasal colonization in younger kids is related to wholesome management teams in research of center ear infections.
Genome polyprotein Antibody |
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1-CSB-PA333180LA01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA362073LA01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA714772LA01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome Polyprotein Antibody |
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20-abx109417 | Abbexa |
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Genome polyprotein Antibody |
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20-abx300967 | Abbexa |
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Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-YP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in Yeast |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQDb0 | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Genome polyprotein Antibody (HRP) |
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20-abx109095 | Abbexa |
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Genome Polyprotein Antibody (Biotin) |
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20-abx105887 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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20-abx106264 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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20-abx107678 | Abbexa |
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Genome polyprotein Antibody (HRP) |
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20-abx300968 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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20-abx300969 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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20-abx300970 | Abbexa |
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Genome Polyprotein Polyclonal Antibody |
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A68253-020 | EpiGentek | 20 ul | EUR 117.7 |
Genome Polyprotein Polyclonal Antibody |
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A68253-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody |
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A68253-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody |
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A68254-020 | EpiGentek | 20 ul | EUR 117.7 |
Genome Polyprotein Polyclonal Antibody |
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A68254-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody |
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A68254-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody |
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A56130-020 | EpiGentek | 20 ul | EUR 117.7 |
Genome Polyprotein Polyclonal Antibody |
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A56130-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody |
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A56130-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody |
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A56743-020 | EpiGentek | 20 ul | EUR 117.7 |
Genome Polyprotein Polyclonal Antibody |
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A56743-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody |
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A56743-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody |
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A56130 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A56743 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A68253 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A68254 | EpiGentek |
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Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA18549B0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA18549C0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA18549D0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA333180LB01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA333180LC01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA333180LD01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA362073LB01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA362073LC01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA362073LD01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA714772LB01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA714772LC01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA714772LD01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Rhinovirus A serotype 89 Genome polyprotein Antibody |
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20-abx109372 | Abbexa |
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Hepatitis A Virus antibody |
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10-2693 | Fitzgerald | 1 mg | EUR 198 |
Description: Mouse Monoclonal Hepatitis A Virus antibody |
Hepatitis A Virus antibody |
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10-H15A | Fitzgerald | 100 ug | EUR 462 |
Description: Mouse monoclonal Hepatitis A Virus antibody |
Hepatitis A Virus antibody |
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10-H15B | Fitzgerald | 100 ug | EUR 462 |
Description: Mouse monoclonal Hepatitis A Virus antibody |
Hepatitis A Virus Antibody |
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abx021766-1mg | Abbexa | 1 mg | EUR 2114.4 |
Hepatitis A Virus Antibody |
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abx021767-1mg | Abbexa | 1 mg | EUR 2890.8 |
Duck Hepatitis Virus (DHV) ELISA Kit |
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abx054976-96tests | Abbexa | 96 tests | EUR 801.6 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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20-abx108723 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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20-abx107303 | Abbexa |
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Human rhinovirus 1A Genome polyprotein |
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1-CSB-YP326367HQA | Cusabio |
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Description: Recombinant Human rhinovirus 1A Genome polyprotein,partial expressed in Yeast |
Genome Polyprotein (HCV-Core) Antibody |
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33487-05111 | AssayPro | 150 ug | EUR 313.2 |
Enterovirus 71 Genome polyprotein Antibody |
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20-abx109758 | Abbexa |
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Goat Anti-Hepatitis A Virus (Strain HM175) IgG |
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HAV11-A | Alpha Diagnostics | 100 ul | EUR 548.4 |
Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 (ORF1) |
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1-CSB-EP327230HGE | Cusabio |
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Description: Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1(ORF1),partial expressed in E.coli |
Duck Hepatitis Virus Antibody (DHV-Ab) ELISA Kit |
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abx054977-96tests | Abbexa | 96 tests | EUR 801.6 |
Hepatitis A Virus (HAV) Antibody |
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abx024089-1mg | Abbexa | 1 mg | EUR 1412.4 |
Hepatitis A Virus (HAV) Antibody |
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abx024090-1mg | Abbexa | 1 mg | EUR 1412.4 |
Hepatitis A Virus (HAV) Antibody |
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abx024091-1mg | Abbexa | 1 mg | EUR 1412.4 |
Hepatitis A Virus protein |
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30R-AH015 | Fitzgerald | 1 ml | EUR 453.6 |
Description: Purified native Hepatitis A Virus protein |
Hepatitis A Virus protein |
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30-1929 | Fitzgerald | 1 ml | EUR 159.6 |
Description: Purified Native Hepatitis A Virus protein |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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20-abx108220 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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20-abx105382 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (FITC) |
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20-abx106801 | Abbexa |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68250-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68250-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68251-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68251-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68252-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68252-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68255-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68255-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68256-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68256-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68257-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68257-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56131-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56131-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56132-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56132-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56133-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56133-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56744-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56744-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56745-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56745-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56746-050 | EpiGentek | 50 ul | EUR 302.5 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56746-100 | EpiGentek | 100 ul | EUR 423.5 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56131 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56132 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56133 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56744 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56745 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56746 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68250 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68251 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68252 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68255 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68256 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68257 | EpiGentek |
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Recombinant Hepatitis C Virus polyprotein, His, E.coli-100ug |
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QP8939-ec-100ug | EnQuireBio | 100ug | EUR 848.4 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-10ug |
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QP8939-ec-10ug | EnQuireBio | 10ug | EUR 391.2 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-1mg |
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QP8939-ec-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-200ug |
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QP8939-ec-200ug | EnQuireBio | 200ug | EUR 1338 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-500ug |
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QP8939-ec-500ug | EnQuireBio | 500ug | EUR 1816.8 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-50ug |
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QP8939-ec-50ug | EnQuireBio | 50ug | EUR 522 |
Virus Hepatitis A Virus (HAV) Protein |
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abx670259-1ml | Abbexa | 1 ml | EUR 427.2 |
Sindbis virus Structural polyprotein |
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1-CSB-CF361018SHZ | Cusabio |
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Description: Recombinant Sindbis virus Structural polyprotein,partial expressed in in vitro E.coli expression system |
Sindbis virus Structural polyprotein |
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1-CSB-CF361018SHZb2 | Cusabio |
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Description: Recombinant Sindbis virus Structural polyprotein,partial expressed in in vitro E.coli expression system |
Turnip mosaic virus Polyprotein |
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1-CSB-EP2708TJM | Cusabio |
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Description: Recombinant Turnip mosaic virus Polyprotein,partial expressed in E.coli |
Mouse antibody for Hepatitis A virus |
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1880 | Virostat | 100 ug | EUR 386.26 |
Description: This is purified Mouse monoclonal antibody against Hepatitis A virus for WB, ELISA. |
Mouse antibody for Hepatitis A virus |
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1885 | Virostat | 100 ug | EUR 386.26 |
Description: This is purified Mouse monoclonal antibody against Hepatitis A virus for WB, ELISA. |
Mouse antibody for Hepatitis A virus |
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1887 | Virostat | 100 ug | EUR 386.26 |
Description: This is purified Mouse monoclonal antibody against Hepatitis A virus for WB, ELISA. |
Mouse antibody for Hepatitis A virus |
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1889 | Virostat | 100 ug | EUR 386.26 |
Description: This is purified Mouse monoclonal antibody against Hepatitis A virus for WB, ELISA. |
Hepatitis A Virus (HAV 2C) Antibody |
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abx018290-100ug | Abbexa | 100 ug | EUR 460.8 |
Hepatitis A Virus (HAV 2C) Antibody |
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abx018291-100ug | Abbexa | 100 ug | EUR 460.8 |
Hepatitis A Virus Strain HM175 Antibody |
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abx022990-1ml | Abbexa | 1 ml | EUR 828 |
Recombinant Hepatitis A Virus VP1 |
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7-07384 | CHI Scientific | 100µg | Ask for price |
Recombinant Hepatitis A Virus VP1 |
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7-07385 | CHI Scientific | 500µg | Ask for price |
Recombinant Hepatitis A Virus VP1 |
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7-07386 | CHI Scientific | 1000µg | Ask for price |
Recombinant Hepatitis A Virus P2C |
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7-07393 | CHI Scientific | 100µg | Ask for price |
Recombinant Hepatitis A Virus P2C |
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7-07394 | CHI Scientific | 500µg | Ask for price |
Recombinant Hepatitis A Virus P2C |
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7-07395 | CHI Scientific | 1000µg | Ask for price |
Recombinant Hepatitis A Virus P3C |
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7-07402 | CHI Scientific | 100µg | Ask for price |
Recombinant Hepatitis A Virus P3C |
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7-07403 | CHI Scientific | 500µg | Ask for price |
Recombinant Hepatitis A Virus P3C |
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7-07404 | CHI Scientific | 1000µg | Ask for price |
Recombinant Hepatitis A Virus VP3 |
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7-07405 | CHI Scientific | 100µg | Ask for price |
Recombinant Hepatitis A Virus VP3 |
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7-07406 | CHI Scientific | 500µg | Ask for price |
Recombinant Hepatitis A Virus VP3 |
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7-07407 | CHI Scientific | 1000µg | Ask for price |
Hepatitis A Virus VP3 Protein |
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20-abx260118 | Abbexa |
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Hepatitis A Virus VP1 Protein |
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20-abx260119 | Abbexa |
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Hepatitis A Virus P2C Protein |
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20-abx260121 | Abbexa |
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Hepatitis A Virus P3C Protein |
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20-abx260122 | Abbexa |
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Hepatitis A Virus (HAV) Antigens |
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HAV17-N-10 | Alpha Diagnostics | 10 ug | Ask for price |
Hepatitis A virus PCR kit |
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PCR-H495-48R | Bioingentech | 50T | EUR 987.6 |
Hepatitis A virus PCR kit |
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PCR-H495-96R | Bioingentech | 100T | EUR 1335.6 |
Genome Polyprotein (HCV-Core) Antibody (Biotin Conjugate) |
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33487-05121 | AssayPro | 150 ug | EUR 442.8 |
HAVCR1 Human, Hepatitis A Virus Cellular Receptor 1 Human Recombinant Protein, HEK |
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PROTQ96D42-1 | BosterBio | Regular: 10ug | EUR 380.4 |
Description: HAVCR1 Human Recombinant produced in HEK cells is a single, glycosylated, polypeptide chain (Ser21-Thr288) containing a total of 283 amino acids, having a calculated molecular mass of 30.5kDa. HAVCR1 is fused to a 2 aa N-terminal linker, a 2 aa C-terminal linker and a 6 aa His tag at C-Terminus. |
HAVCR2 Hepatitis A Virus Cellular Receptor 2 Human Recombinant Protein |
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PROTQ8TDQ0-1 | BosterBio | Regular: 20ug | EUR 380.4 |
Description: Recombinant Human HAVCR2 produced in E. Coli is a single polypeptide chain containing 206 amino acids (aa 22-202) and having a molecular mass of 22.7kDa.;HAVCR2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Rabbit Anti-Hemagglutinin HA1 Influenza A Virus (H11N2; A/duck/Yangzhou/906/2002) IgG |
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H11N2-01-A | Alpha Diagnostics | 100 ul | EUR 578.4 |
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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20-abx109861 | Abbexa |
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Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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20-abx007199 | Abbexa |
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Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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abx027749-400ul | Abbexa | 400 ul | EUR 627.6 |
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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abx027749-80l | Abbexa | 80 µl | EUR 343.2 |
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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20-abx339995 | Abbexa |
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Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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20-abx339771 | Abbexa |
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Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody |
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20-abx318372 | Abbexa |
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Hepatitis A Virus Cellular Receptor 1 Protein |
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20-abx262425 | Abbexa |
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Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3408 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2452.8 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1693.2 |
Description: YFV Genome polyprotein, recombinant protein. |
Hepatitis A Virus Cellular Receptor 1 (KIM-1) Antibody |
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20-abx102459 | Abbexa |
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Hepatitis A Virus Cellular Receptor 1 (KIM-1) Antibody |
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abx023704-1mg | Abbexa | 1 mg | EUR 1053.6 |
Hepatitis A Virus Cellular Receptor 1 (KIM-1) Antibody |
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abx023705-1mg | Abbexa | 1 mg | EUR 1053.6 |
MBD1 Polyclonal Antibody |
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A-1006 | EpiGentek |
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PRDM4 Polyclonal Antibody |
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A-2004 | EpiGentek |
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PRDM5 Polyclonal Antibody |
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A-2005 | EpiGentek |
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PRDM10 Polyclonal Antibody |
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A-2010 | EpiGentek |
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PRDM11 Polyclonal Antibody |
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A-2011 | EpiGentek |
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PRDM13 Polyclonal Antibody |
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A-2013 | EpiGentek |
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PRDM16 Polyclonal Antibody |
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A-2016 | EpiGentek |
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PRDM17 Polyclonal Antibody |
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A-2017 | EpiGentek |
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EZH1 Polyclonal Antibody |
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A-2018 | EpiGentek |
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HSF1 Polyclonal Antibody |
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A-2401 | EpiGentek |
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PRMT3 Polyclonal Antibody |
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A-3003 | EpiGentek |
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SET1 Polyclonal Antibody |
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A-3011 | EpiGentek |
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SET07 Polyclonal Antibody |
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A-3013 | EpiGentek |
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LSD1 Polyclonal Antibody |
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A-3018 | EpiGentek |
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HDAC10 Polyclonal Antibody |
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A-4010 | EpiGentek |
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PCAF Polyclonal Antibody |
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A-4012 | EpiGentek |
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Mouse Hepatitis A virus cellular receptor 1 homolog (Havcr1) |
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1-CSB-RP171094m | Cusabio |
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Description: Recombinant Mouse Hepatitis A virus cellular receptor 1 homolog(Havcr1),partial expressed in E.coli |
DNMT3A Polyclonal Antibody |
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A-1003 | EpiGentek |
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DNMT3B Polyclonal Antibody |
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A-1004 | EpiGentek |
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DNMT3L Polyclonal Antibody |
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A-1005 | EpiGentek |
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MBD3 Polyclonal Antibody |
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A-1008 | EpiGentek |
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MGMT Polyclonal Antibody |
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A-1010 | EpiGentek |
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MeCP2 Polyclonal Antibody |
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A-1012 | EpiGentek |
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TET1 Polyclonal Antibody |
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A-1020 | EpiGentek |
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DNMT1 Polyclonal Antibody |
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A-1700 | EpiGentek |
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TET2 Polyclonal Antibody |
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A-1701 | EpiGentek |
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MBD2 Polyclonal Antibody |
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A-1713 | EpiGentek |
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PRDM2 Polyclonal Antibody |
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A-2002 | EpiGentek |
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PRDM3 Polyclonal Antibody |
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A-2003 | EpiGentek |
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PRDM6 Polyclonal Antibody |
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A-2006 | EpiGentek |
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PRDM12 Polyclonal Antibody |
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A-2012 | EpiGentek |
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PRDM14 Polyclonal Antibody |
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A-2014 | EpiGentek |
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EZH2 Polyclonal Antibody |
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A-2019 | EpiGentek |
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EED Polyclonal Antibody |
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A-2020 | EpiGentek |
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Ini1 Polyclonal Antibody |
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A-2026 | EpiGentek |
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CBX5 Polyclonal Antibody |
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A-2701 | EpiGentek |
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EGLN1 Polyclonal Antibody |
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A-2702 | EpiGentek |
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RBBP4 Polyclonal Antibody |
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A-2703 | EpiGentek |
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SIN3A Polyclonal Antibody |
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A-2704 | EpiGentek |
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CTBP1 Polyclonal Antibody |
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A-2705 | EpiGentek |
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PADI4 Polyclonal Antibody |
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A-2706 | EpiGentek |
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SMARCA5 Polyclonal Antibody |
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A-2707 | EpiGentek |
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IDH1 Polyclonal Antibody |
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A-2708 | EpiGentek |
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CHD4 Polyclonal Antibody |
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A-2709 | EpiGentek |
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CHAF1A Polyclonal Antibody |
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A-2710 | EpiGentek |
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BRD7 Polyclonal Antibody |
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A-2712 | EpiGentek |
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UHRF1 Polyclonal Antibody |
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A-2714 | EpiGentek |
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UHRF2 Polyclonal Antibody |
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A-2715 | EpiGentek |
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SMARCE1 Polyclonal Antibody |
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A-2716 | EpiGentek |
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ACTL6A Polyclonal Antibody |
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A-2717 | EpiGentek |
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MPG Polyclonal Antibody |
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A-2718 | EpiGentek |
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HIF1AN Polyclonal Antibody |
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A-2719 | EpiGentek |
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RNF2 Polyclonal Antibody |
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A-2720 | EpiGentek |
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PCGF6 Polyclonal Antibody |
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A-2721 | EpiGentek |
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SMARCB1 Polyclonal Antibody |
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A-2722 | EpiGentek |
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ALKBH3 Polyclonal Antibody |
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A-2723 | EpiGentek |
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BBOX1 Polyclonal Antibody |
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A-2724 | EpiGentek |
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BTAF1 Polyclonal Antibody |
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A-2725 | EpiGentek |
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CXXC1 Polyclonal Antibody |
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A-2726 | EpiGentek |
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KDM4B Polyclonal Antibody |
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A-2727 | EpiGentek |
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HELLS Polyclonal Antibody |
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A-2728 | EpiGentek |
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ING3 Polyclonal Antibody |
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A-2729 | EpiGentek |
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ING4 Polyclonal Antibody |
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A-2730 | EpiGentek |
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PHC1 Polyclonal Antibody |
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A-2731 | EpiGentek |
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SMARCAD1 Polyclonal Antibody |
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A-2732 | EpiGentek |
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×
Our evaluation of 28 genomes revealed a outstanding stability of D. pigrum strains colonizing individuals in america throughout a 20-year span. We subsequently recognized components that may affect this stability, together with genomic stability, phage predators, the function of MGEs in strain-level variation, and defenses towards MGEs. Lastly, these D. pigrum strains additionally lacked predicted virulence components. Total, these findings add extra help to the potential for D. pigrum as a therapeutic bacterium.
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