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Sex-dependent gene co-expression in the human body
Many pathophysiological mechanisms in human well being and illness are depending on intercourse. Methods biology approaches are efficiently used to decipher human illness etiology, but the impact of intercourse on gene community biology is generally unknown.
To deal with this, we used RNA-sequencing knowledge of over 700 people spanning 24 tissues from the Genotype-Tissue Expression challenge to generate a whole-body gene co-expression map and quantified the intercourse variations per tissue.
We discovered that of the 13,787 genes analyzed in 24 tissues, 29.5% of the gene co-expression is influenced by intercourse. For instance, skeletal muscle was predominantly enriched with genes co-expressed stronger in males, whereas thyroid primarily contained genes co-expressed stronger in females. This was accompanied by constant sex variations in pathway enrichment, together with hypoxia, epithelial-to-mesenchymal transition, and irritation over the human physique.
Moreover, multi-organ analyses revealed constant sex-dependent gene co-expression over quite a few tissues which was accompanied by enrichment of transcription issue binding motifs within the promoters of those genes.
Lastly, we present that many sex-biased genes are related to sex-biased illnesses, similar to autoimmunity and most cancers, and extra usually the goal of FDA-approved medication than non-sexbiased genes. Our examine means that intercourse impacts organic gene networks by variations in gene co-expression and that spotlight to the impact of intercourse on organic responses to medical medication is warranted.
Structural variants are a serious supply of gene expression variations in people and infrequently have an effect on a number of close by genes
Structural variants (SVs) are an necessary supply of human genome range however their practical results should not properly understood. We mapped 61,668 SVs in 613 people with deep genome sequencing knowledge from the GTEx challenge and measured their results on gene expression. We estimate that widespread SVs are causal at 2.66% of eQTLs, which is a 10.5-fold enrichment relative to their abundance within the genome and in line with prior work utilizing smaller pattern sizes.
Duplications and deletions have been probably the most impactful variant sorts, whereas the contribution of cell ingredient insertions was small (0.12% of eQTLs, 1.9-fold enriched). Multi-tissue evaluation of expression results revealed that gene-altering SVs present considerably extra constitutive results than different variant sorts, with 62.09% of coding SV-eQTLs energetic in all tissues with identified eQTL exercise in comparison with 23.08% of coding SNV- and indel-eQTLs, whereas noncoding SVs, SNVs and indels present broadly comparable patterns.
We additionally recognized 539 uncommon SVs related to close by gene expression outliers. Of those, 62.34% are noncoding SVs that present sturdy results on gene expression but modest enrichment at identified regulatory components, demonstrating that uncommon noncoding SVs are a serious supply of gene expression variations however stay troublesome to foretell from present annotations.
Each widespread and uncommon noncoding SVs usually present sturdy regional results on the expression of a number of genes: SV-eQTLs have an effect on a median of 1.82 close by genes in comparison with 1.09 genes affected by SNV- and indel-eQTLs, and 21.34% of uncommon expression-altering SVs present sturdy results on 2-9 completely different genes. We additionally observe important results on uncommon gene expression changes extending 1 Mb from the SV. This offers a mechanism by which particular person noncoding SVs could have sturdy or pleiotropic results on phenotypic variation and illness.
Technology of ‘designer erythroblasts’ missing a number of blood group programs from CRISPR/Cas9 gene-edited human-induced pluripotent stem cells
Regardless of the current developments in transfusion drugs, crimson blood cell (RBC) alloimmunization stays a problem for multiparous ladies and chronically transfused sufferers. At instances, diagnostic laboratories depend upon difficult-to-procure uncommon reagent RBCs for the identification of various alloantibodies in such topics.
We’ve got addressed this difficulty by creating erythroblasts with customized phenotypes (Rh null, GPB null and Kx null/Kell low) utilizing CRISPR/Cas9 gene-editing of a human induced pluripotent stem cell (hiPSC) father or mother line (OT1-1) for the blood group system genes: RHAG, GYPB and XK. Information RNAs have been cloned into Cas9-puromycin expression vector and transfected into OT1-1.
Genotyping was carried out to pick puromycin-resistant hiPSC KOs. CRISPR/Cas9 gene-editing resulted within the profitable technology of three KO strains, RHAG KO, GYPB KO and XK KO. The OT1-1 cell line, in addition to the three KO hiPSC strains, have been differentiated into CD34+ CD41+ CD235ab+ hematopoietic progenitor cells (HPCs) and subsequently to erythroblasts.
Native OT1-1 erythroblasts have been optimistic for the expression of Rh, MNS, Kell and H blood group programs. Differentiation of RHAG KO, GYPB KO and XK KO resulted within the formation of Rh null, GPB null and Kx null/Kell low erythroblasts, respectively. OT1-1 in addition to the three KO erythroblasts remained optimistic for RBC markers-CD71 and BAND3.
Erythroblasts have been principally on the polychromatic/ orthochromatic stage of differentiation. As much as ~400-fold enhance in erythroblasts derived from HPCs was noticed. The provision of customized erythroblasts generated from CRISPR/Cas9 gene-edited hiPSC needs to be a helpful addition to the instruments at present used for the detection of clinically necessary crimson cell alloantibodies.
Genomic Stability and Genetic Protection Methods in Dolosigranulum pigrum, a Candidate Useful Bacterium from the Human Microbiome
Dolosigranulum pigrum is positively related to indicators of well being in a number of epidemiological research of human nasal microbiota. Data of the essential biology of D. pigrum is a prerequisite for evaluating its potential for future therapeutic use; nevertheless, such knowledge are very restricted. To realize perception into D. pigrum‘s chromosomal construction, pangenome, and genomic stability, we in contrast the genomes of 28 D. pigrum strains that have been collected throughout 20 years.
Phylogenomic evaluation confirmed carefully associated strains circulating over this era and closure of 19 genomes revealed extremely conserved chromosomal synteny. Gene clusters concerned within the mobilome and in protection towards cell genetic components (MGEs) have been enriched within the accent genome versus the core genome.
A scientific evaluation for MGEs recognized the primary candidate D. pigrum prophage and insertion sequence. A scientific evaluation for genetic components that restrict the unfold of MGEs, together with restriction modification (RM), CRISPR-Cas, and deity-named protection programs, revealed strain-level range in host protection programs that localized to particular genomic websites, together with one RM system scorching spot. Evaluation of CRISPR spacers pointed to a wealth of MGEs towards which D. pigrum defends itself.
These outcomes reveal a task for horizontal gene switch and cell genetic components in pressure diversification whereas highlighting that in D. pigrum this happens inside the context of a extremely secure chromosomal group protected by quite a lot of protection mechanisms. IMPORTANCE Dolosigranulum pigrum is a candidate helpful bacterium with potential for future therapeutic use. That is based mostly on its optimistic associations with traits of well being in a number of research of human nasal microbiota throughout the span of human life.
For instance, excessive ranges of D. pigrum nasal colonization in adults predicts the absence of Staphylococcus aureus nasal colonization. Additionally, D. pigrum nasal colonization in younger kids is related to wholesome management teams in research of center ear infections.
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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CSB-MP333180HFD | Cusabio | 4998 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial |
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AP73727 | SAB | each | Ask for price |
Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial |
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AP73728 | SAB | each | Ask for price |
Hepatitis C Genome polyprotein |
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1-CSB-RP184674Ba | Cusabio |
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Description: Recombinant Hepatitis C Genome polyprotein expressed in E.coli |
Recombinant Hepatitis C virus genotype 1a (isolate 1) (HCV) Genome polyprotein(E1),partial |
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AP70969 | SAB | 1mg | EUR 2826 |
Recombinant Hepatitis C Genome polyprotein |
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CSB-RP184674Ba | Cusabio | 5430 mg | Ask for price |
Recombinant Hepatitis C Genome polyprotein |
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RPC24458-100ug | Biomatik Corporation | 100ug | EUR 721.6 |
Recombinant Hepatitis C Genome polyprotein |
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RPC24458-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-100g | Abbexa | 100 µg | Ask for price |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-20g | Abbexa | 20 µg | EUR 250 |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-50g | Abbexa | 50 µg | EUR 350 |
Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 (ORF1) |
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1-CSB-EP327230HGE | Cusabio |
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Description: Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1(ORF1),partial expressed in E.coli |
Japanese Encephalitis Virus Genome polyprotein Antibody |
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abx345000-100l | Abbexa | 100 µl | EUR 350 |
Japanese Encephalitis Virus Genome polyprotein Antibody |
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abx345000-50l | Abbexa | 50 µl | EUR 250 |
Bovine Viral Diarrhea Virus Genome Polyprotein Antibody |
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abx345377-100tests | Abbexa | 100 tests | EUR 250 |
Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 (ORF1) |
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AP71039 | SAB | 1mg | EUR 2826 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-1mg |
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QP8939-ec-1mg | EnQuireBio | 1mg | EUR 2763.6 |
Yellow fever virus Genome polyprotein |
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1-CSB-EP365905YAC1 | Cusabio |
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Description: Recombinant Yellow fever virus Genome polyprotein,partial expressed in E.coli |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-10ug |
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QP8939-ec-10ug | EnQuireBio | 10ug | EUR 391.2 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-50ug |
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QP8939-ec-50ug | EnQuireBio | 50ug | EUR 522 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-100ug |
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QP8939-ec-100ug | EnQuireBio | 100ug | EUR 848.4 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-200ug |
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QP8939-ec-200ug | EnQuireBio | 200ug | EUR 1338 |
Recombinant Hepatitis C Virus polyprotein, His, E.coli-500ug |
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QP8939-ec-500ug | EnQuireBio | 500ug | EUR 1816.8 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) polyprotein, His-SUMO, Mammal-1mg |
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QP6996-1mg | EnQuireBio | 1mg | EUR 3037.2 |
Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 (ORF1), partial |
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CSB-EP327230HGE | Cusabio | 2937 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1b (strain HC-J4) polyprotein, His, Yeast-1mg |
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QP9739-ye-1mg | EnQuireBio | 1mg | EUR 3296.4 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) polyprotein, His-SUMO, Mammal-10ug |
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QP6996-10ug | EnQuireBio | 10ug | EUR 426 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) polyprotein, His-SUMO, Mammal-200ug |
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QP6996-200ug | EnQuireBio | 200ug | EUR 1468.8 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) polyprotein, His-SUMO, Mammal-20ug |
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QP6996-20ug | EnQuireBio | 20ug | EUR 523.2 |
Recombinant Hepatitis C virus genotype 1a (isolate 1) polyprotein, His-SUMO, Mammal-500ug |
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QP6996-500ug | EnQuireBio | 500ug | EUR 1936.8 |
Recombinant Hepatitis C virus genotype 1b (strain HC-J4) polyprotein, His, Yeast-100ug |
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QP9739-ye-100ug | EnQuireBio | 100ug | EUR 945.6 |
Recombinant Hepatitis C virus genotype 1b (strain HC-J4) polyprotein, His, Yeast-10ug |
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QP9739-ye-10ug | EnQuireBio | 10ug | EUR 434.4 |
Recombinant Hepatitis C virus genotype 1b (strain HC-J4) polyprotein, His, Yeast-200ug |
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QP9739-ye-200ug | EnQuireBio | 200ug | EUR 1512 |
Recombinant Hepatitis C virus genotype 1b (strain HC-J4) polyprotein, His, Yeast-500ug |
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QP9739-ye-500ug | EnQuireBio | 500ug | EUR 2164.8 |
Recombinant Hepatitis C virus genotype 1b (strain HC-J4) polyprotein, His, Yeast-50ug |
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QP9739-ye-50ug | EnQuireBio | 50ug | EUR 576 |
Japanese encephalitis virus Genome polyprotein |
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1-CSB-EP189574Ba | Cusabio |
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Description: Recombinant Japanese encephalitis virus Genome polyprotein,partial expressed in E.coli |
Recombinant Zika virus Genome polyprotein, partial |
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CSB-EP3643GOZ3 | Cusabio | 7769 mg | Ask for price |
Genome polyprotein Antibody |
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20-abx300967 | Abbexa |
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Genome polyprotein Antibody |
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1-CSB-PA18549A0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA333180LA01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA362073LA01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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CSB-PA4643XA11GSV | Cusabio | 100ul / 50ul | EUR 299 |
Description: Genome polyprotein |
Genome polyprotein Antibody |
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CSB-PA4644XA11GSW | Cusabio | 100ul / 50ul | EUR 299 |
Description: Genome polyprotein |
Genome polyprotein Antibody |
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1-CSB-PA714772LA01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome Polyprotein Antibody |
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20-abx109417 | Abbexa |
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Genome polyprotein Antibody |
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abx300967-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody |
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abx300967-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody |
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abx300967-50g | Abbexa | 50 µg | EUR 250 |
Genome Polyprotein Antibody |
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abx109417-100l | Abbexa | 100 µl | EUR 162.5 |
Recombinant West Nile virus Genome polyprotein, partial |
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CSB-EP356974WAF2 | Cusabio | 9323 mg | Ask for price |
Recombinant Yellow fever virus Genome polyprotein, partial |
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CSB-EP365905YAC1 | Cusabio | 3485 mg | Ask for price |
Recombinant Yellow fever virus Genome polyprotein,partial |
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AP77947 | SAB | 1mg | EUR 2826 |
Recombinant Yellow fever virus Genome polyprotein,partial |
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RPC22821-100ug | Biomatik Corporation | 100ug | EUR 721.6 |
Recombinant Yellow fever virus Genome polyprotein,partial |
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RPC22821-1mg | Biomatik Corporation | 1mg | EUR 2884.7 |
Recombinant Yellow fever virus Genome polyprotein,partial |
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RPC22821-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Genome polyprotein Antibody (HRP) |
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20-abx300968 | Abbexa |
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Genome polyprotein Antibody (HRP) |
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20-abx109095 | Abbexa |
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Genome polyprotein Antibody (HRP) |
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abx300968-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (HRP) |
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abx109095-100l | Abbexa | 100 µl | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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20-abx300969 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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20-abx107678 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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abx300969-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (FITC) |
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abx300969-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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abx300969-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (FITC) |
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abx107678-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (FITC) |
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abx107678-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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abx107678-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (Biotin) |
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20-abx300970 | Abbexa |
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Genome Polyprotein Antibody (Biotin) |
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20-abx105887 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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20-abx106264 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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abx300970-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (Biotin) |
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abx300970-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (Biotin) |
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abx300970-50g | Abbexa | 50 µg | EUR 250 |
Genome Polyprotein Antibody (Biotin) |
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abx105887-100g | Abbexa | 100 µg | EUR 362.5 |
Genome Polyprotein Antibody (Biotin) |
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abx105887-20g | Abbexa | 20 µg | EUR 162.5 |
Genome Polyprotein Antibody (Biotin) |
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abx105887-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (Biotin) |
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abx106264-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (Biotin) |
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abx106264-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (Biotin) |
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abx106264-50g | Abbexa | 50 µg | EUR 250 |
Recombinant Japanese encephalitis virus Genome polyprotein, partial |
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CSB-EP189574Ba | Cusabio | 2537 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein , partial |
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CSB-YP312464BKX1 | Cusabio | 6140 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein, partial |
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CSB-EP312464BKX1 | Cusabio | 2704 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein, partial |
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CSB-BP312464BKX1 | Cusabio | 139 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein,partial |
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RPC28130-100ug | Biomatik Corporation | 100ug | EUR 1544.5 |
Recombinant Bovine viral diarrhea virus Genome polyprotein,partial |
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RPC28130-20ug | Biomatik Corporation | 20ug | EUR 580.8 |
Recombinant Dengue virus type 2 Genome polyprotein, partial |
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CSB-YP530838DCF | Cusabio | 7267 mg | Ask for price |
Recombinant Classical swine fever virus Genome polyprotein, partial |
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CSB-YP4953GLU | Cusabio | 12085 mg | Ask for price |
Recombinant St. louis encephalitis virus Genome polyprotein, partial |
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CSB-EP357746SKT | Cusabio | 9322 mg | Ask for price |
Recombinant Classical swine fever virus Genome polyprotein, partial |
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CSB-EP4953GLU | Cusabio | 11663 mg | Ask for price |
Recombinant Classical swine fever virus Genome polyprotein, partial |
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CSB-BP4334GLU | Cusabio | 10139 mg | Ask for price |
Classical Swine Fever Virus Genome Polyprotein (CSFV-GP) Protein |
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abx694331-10nmol | Abbexa | 10 nmol | EUR 625 |
Classical Swine Fever Virus Genome Polyprotein (CSFV-GP) Protein |
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abx694331-5nmol | Abbexa | 5 nmol | EUR 425 |
Rhinovirus A serotype 89 Genome polyprotein Antibody |
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20-abx109372 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody |
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abx109372-100l | Abbexa | 100 µl | EUR 162.5 |
Recombinant Tick-borne encephalitis virus Genome polyprotein, partial |
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CSB-EP3056GKR | Cusabio | 2646 mg | Ask for price |
Genome Polyprotein Polyclonal Antibody |
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A56130 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A56743 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A68253 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A68254 | EpiGentek |
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Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA18549B0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA333180LB01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA362073LB01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA714772LB01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is HRP conjugated. Tested in the following application: ELISA |
Enterovirus 71 Genome polyprotein Antibody |
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20-abx109758 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody |
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abx109758-100l | Abbexa | 100 µl | EUR 162.5 |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA18549C0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA333180LC01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA362073LC01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA714772LC01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is FITC conjugated. Tested in the following application: ELISA |
Porcine Teschovirus 1 Genome Polyprotein Antibody |
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abx345841-100g | Abbexa | 100 µg | Ask for price |
Porcine Teschovirus 1 Genome Polyprotein Antibody |
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abx345841-20g | Abbexa | 20 µg | EUR 250 |
Porcine Teschovirus 1 Genome Polyprotein Antibody |
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abx345841-50g | Abbexa | 50 µg | EUR 350 |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA18549D0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA333180LD01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA362073LD01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA714772LD01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Recombinant Dengue virus type 2 Genome polyprotein (Q1642N), partial |
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CSB-EP3044GLD(M) | Cusabio | 11736 mg | Ask for price |
Genome Polyprotein (HCV-Core) Antibody |
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33487-05111 | AssayPro | 150 ug | EUR 215 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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20-abx108723 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-100g | Abbexa | 100 µg | EUR 362.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-20g | Abbexa | 20 µg | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-50g | Abbexa | 50 µg | EUR 250 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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20-abx107303 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-100g | Abbexa | 100 µg | EUR 362.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-20g | Abbexa | 20 µg | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-50g | Abbexa | 50 µg | EUR 250 |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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20-abx108220 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (HRP) |
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abx108220-100g | Abbexa | 100 µg | EUR 362.5 |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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abx108220-20g | Abbexa | 20 µg | EUR 162.5 |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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abx108220-50g | Abbexa | 50 µg | EUR 250 |
Enterovirus 71 Genome polyprotein Antibody (FITC) |
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20-abx106801 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (FITC) |
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abx106801-100g | Abbexa | 100 µg | EUR 362.5 |
Enterovirus 71 Genome polyprotein Antibody (FITC) |
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abx106801-20g | Abbexa | 20 µg | EUR 162.5 |
Enterovirus 71 Genome polyprotein Antibody (FITC) |
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abx106801-50g | Abbexa | 50 µg | EUR 250 |
Recombinant Dengue virus 2 Genome polyprotein (T2493G,G2494S,I2762T), partial |
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CSB-EP2239GLD(M) | Cusabio | 11735 mg | Ask for price |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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20-abx105382 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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abx105382-100g | Abbexa | 100 µg | EUR 362.5 |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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abx105382-20g | Abbexa | 20 µg | EUR 162.5 |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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abx105382-50g | Abbexa | 50 µg | EUR 250 |
Anti-CrPV Genome polyprotein Polyclonal Antibody |
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AB1I144 | Antagene | 0.1mg | EUR 399 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56131 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56744 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68252 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68255 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56132 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56745 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68251 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68256 | EpiGentek |
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Recombinant Tick-borne encephalitis virus European subtype Genome polyprotein, partial |
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CSB-EP318509TEM | Cusabio | 11863 mg | Ask for price |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56133 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56746 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68250 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68257 | EpiGentek |
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Genome Polyprotein (HCV-Core) Antibody (Biotin Conjugate) |
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33487-05121 | AssayPro | 150 ug | EUR 315 |
Recombinant Tick-borne encephalitis virus Far Eastern subtype Genome polyprotein, partial |
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CSB-EP357187TEN | Cusabio | 11862 mg | Ask for price |
Recombinant Tick-borne encephalitis virus Far Eastern subtype Genome polyprotein, partial |
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CSB-EP357187TENa0 | Cusabio | 11843 mg | Ask for price |
Recombinant Tick-borne encephalitis virus Far Eastern subtype Genome polyprotein, partial |
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CSB-EP357187TENc7 | Cusabio | 11839 mg | Ask for price |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-YP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in Yeast |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQDb0 | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Human rhinovirus 1A Genome polyprotein |
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1-CSB-YP326367HQA | Cusabio |
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Description: Recombinant Human rhinovirus 1A Genome polyprotein,partial expressed in Yeast |
Duck Hepatitis Virus 1 Antibody (DHV-1 Ab) ELISA Kit |
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abx054977-100g | Abbexa | 100 µg | Ask for price |
Duck Hepatitis Virus 1 Antibody (DHV-1 Ab) ELISA Kit |
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abx054977-10g | Abbexa | 10 µg | EUR 493.75 |
Duck Hepatitis Virus 1 Antibody (DHV-1 Ab) ELISA Kit |
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abx054977-50g | Abbexa | 50 µg | Ask for price |
Recombinant Human parechovirus 1 Genome polyprotein |
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CSB-YP734409HCAV | Cusabio | 9748 mg | Ask for price |
Duck Hepatitis Virus Antibody (DHV-Ab) ELISA Kit |
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abx054977-96tests | Abbexa | 96 tests | EUR 801.6 |
Genome Polyprotein (HCV-Core) AssayLite™ Antibody (RPE Conjugate) |
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33487-05151 | AssayPro | 150 ug | EUR 370 |
Genome Polyprotein (HCV-Core) AssayLite™ Antibody (APC Conjugate) |
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33487-05161 | AssayPro | 150 ug | EUR 370 |
Genome Polyprotein (HCV-Core) AssayLite™ Antibody (FITC Conjugate) |
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33487-05141 | AssayPro | 150 ug | EUR 370 |
Genome Polyprotein (HCV-Core) AssayLite™ Antibody (PerCP Conjugate) |
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33487-05171 | AssayPro | 150 ug | EUR 410 |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3408 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2452.8 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1693.2 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant JEV Genome polyprotein (aa 2528-3432) Protein |
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VAng-Wyb3447-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 9926.4 |
Description: Japanese encephalitis virus (strain Jaoars982) Genome polyprotein, recombinant protein. |
Duck Hepatitis Virus (DHV) ELISA Kit |
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abx054976-96tests | Abbexa | 96 tests | EUR 801.6 |
Duck Hepatitis Virus (DHV) ELISA Kit |
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abx054976-100g | Abbexa | 100 µg | Ask for price |
Duck Hepatitis Virus (DHV) ELISA Kit |
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abx054976-10g | Abbexa | 10 µg | EUR 493.75 |
Duck Hepatitis Virus (DHV) ELISA Kit |
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abx054976-50g | Abbexa | 50 µg | Ask for price |
Recombinant Human parechovirus 1 Genome polyprotein, partial |
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CSB-EP734409HCAV | Cusabio | 9651 mg | Ask for price |
Recombinant hepatitis Non-structural polyprotein pORF1 Protein, His, E.coli-10ug |
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QP7125-10ug | EnQuireBio | 10ug | EUR 426 |
Recombinant hepatitis Non-structural polyprotein pORF1 Protein, His, E.coli-1mg |
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QP7125-1mg | EnQuireBio | 1mg | EUR 3037.2 |
Recombinant hepatitis Non-structural polyprotein pORF1 Protein, His, E.coli-50ug |
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QP7125-50ug | EnQuireBio | 50ug | EUR 567.6 |
Recombinant YFV Genome polyprotein (NS4A) Protein (aa 1-3412) |
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VAng-Cr6545-inquire | Creative Biolabs | inquire | Ask for price |
Description: YFV (isolate Uganda/A7094A4/1948) Genome polyprotein (NS4A), recombinant protein. |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLA | Cusabio | 7385 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLAa2 | Cusabio | 7384 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLAe0 | Cusabio | 7511 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLAe1 | Cusabio | 7917 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28548-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28548-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28548-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28549-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28549-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28549-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Recombinant Human Genome polyprotein, His, Yeast-1mg |
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QP7370-ye-1mg | EnQuireBio | 1mg | EUR 2262 |
Recombinant hepatitis Non-structural polyprotein pORF1 Protein, His, E.coli-100ug |
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QP7125-100ug | EnQuireBio | 100ug | EUR 925.2 |
Recombinant hepatitis Non-structural polyprotein pORF1 Protein, His, E.coli-200ug |
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QP7125-200ug | EnQuireBio | 200ug | EUR 1468.8 |
Recombinant hepatitis Non-structural polyprotein pORF1 Protein, His, E.coli-500ug |
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QP7125-500ug | EnQuireBio | 500ug | EUR 1936.8 |
Recombinant Coxsackievirus B3 Genome polyprotein, partial |
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CSB-EP361017CRM1 | Cusabio | 8884 mg | Ask for price |
Recombinant Human Genome polyprotein, His, Yeast-10ug |
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QP7370-ye-10ug | EnQuireBio | 10ug | EUR 283.2 |
Recombinant Human Genome polyprotein, His, Yeast-50ug |
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QP7370-ye-50ug | EnQuireBio | 50ug | EUR 358.8 |
Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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VAng-Cr6541-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 5751.6 |
Description: YFV Genome polyprotein, partial, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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VAng-Cr6541-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3657.6 |
Description: YFV Genome polyprotein, partial, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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VAng-Cr6541-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1083.6 |
Description: YFV Genome polyprotein, partial, recombinant protein. |
Recombinant Human Genome polyprotein, His, Yeast-100ug |
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QP7370-ye-100ug | EnQuireBio | 100ug | EUR 576 |
Recombinant Human Genome polyprotein, His, Yeast-200ug |
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QP7370-ye-200ug | EnQuireBio | 200ug | EUR 892.8 |
Recombinant Human Genome polyprotein, His, Yeast-500ug |
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QP7370-ye-500ug | EnQuireBio | 500ug | EUR 1447.2 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-YP362073HQD | Cusabio | 6387 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-EP362073HQD | Cusabio | 3389 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-EP362073HQDb0 | Cusabio | 3390 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP71163 | SAB | 1mg | EUR 1978 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP72984 | SAB | each | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP77542 | SAB | 1mg | EUR 1978 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-100ug | Biomatik Corporation | 100ug | EUR 460.9 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-1mg | Biomatik Corporation | 1mg | EUR 2237.8 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-20ug | Biomatik Corporation | 20ug | EUR 258.7 |
Duck virus hepatitis antibody(DVH-Ab) Elisa kit |
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EK781011 | AFG Bioscience LLC | 96 Wells | EUR 0.99 |
Duck virus hepatitis antibody(DVH-Ab) ELISA Kit |
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SL0018Du | Sunlong | - | EUR 528 |
OPCA05394-20UG - GENOME POLYPROTEIN Recombinant Protein (isolate 1) |
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OPCA05394-20UG | Aviva Systems Biology | 20ug | EUR 339 |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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CSB-YP326367HQA | Cusabio | 6222 mg | Ask for price |
×
Our evaluation of 28 genomes revealed a outstanding stability of D. pigrum strains colonizing individuals in america throughout a 20-year span. We subsequently recognized components that may affect this stability, together with genomic stability, phage predators, the function of MGEs in strain-level variation, and defenses towards MGEs. Lastly, these D. pigrum strains additionally lacked predicted virulence components. Total, these findings add extra help to the potential for D. pigrum as a therapeutic bacterium.
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