Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism
Alcohol use disorder (AUD) demands huge toll on individuals, families, and communities. Genetic factors determine up to 60% of the individual’s risk of developing alcohol habits problematic. AUD effective prevention and treatment requires knowledge of the genes that the predisposition to alcoholism, alcohol plays a role in the response, and / or contribute to the development of addiction. As genetic and behavioral highly tractable model organism and translated, Drosophila melanogaster has proved valuable for uncovering important gene and mechanistic pathways that have clear human orthologs and that helps explain the complexities of addiction.
vinegar flies show very strong face and validity of the mechanistic model for AUDs, allowing a lot of progress in efforts to understand human genetic involvement in this disease. This progress occurs through an approach that basically fall into one of two categories: (1) finding candidate genes through an associate research of the human genome (GWAS), transcriptomics tissue post-mortem from patients AUD, or connection physiologically relevant, then use reverse genetics fly to validate the role of candidate genes and investigate their molecular function in the context of alcohol.
Utilize the flies to find candidate genes through unbiased screen, GWAS, quantitative trait loci analysis, transcriptomics, or the study of a single gene, and then validates their translational role in human genetic survey. In this review, we highlight the utility of Drosophila as a model for alcoholism by surveying recent advances in our understanding of human AUDs generated from various approaches. We summarize the genes preserved in alcohol-related functions between humans and flies. We also provide an insight into some of the advantages and limitations of this approach. Overall, this review shows how Drosophila have and can be used to answer important questions about the genetics of alcoholism.
Genetic and environmental determinants of human TCR repertoire diversity
T cell discrimination of self and non-self is the basis of the adaptive immune response, and is regulated by the interaction between T cell receptors (TCRs) and their cognate ligands presented by major histocompatibility molecules (MHC). However, the impact of host immunogenetic variation on the diversity of the TCR repertoire is still unclear. Here, we analyzed a cohort of 666 individuals with TCR repertoire sequencing.
Recombinant Human rhinovirus 1A Genome polyprotein,partial |
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RPC25135-100ug | Biomatik Corporation | 100ug | EUR 573.1 |
Recombinant Human rhinovirus 1A Genome polyprotein,partial |
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RPC25135-20ug | Biomatik Corporation | 20ug | EUR 288.8 |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-YP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in Yeast |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQDb0 | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Recombinant Human rhinovirus 1B Genome polyprotein, partial |
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CSB-EP320160HQB | Cusabio | 10401 mg | Ask for price |
Rhinovirus A serotype 89 Genome polyprotein Antibody |
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20-abx109372 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody |
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abx109372-100l | Abbexa | 100 µl | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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20-abx108723 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-100g | Abbexa | 100 µg | EUR 362.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-20g | Abbexa | 20 µg | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-50g | Abbexa | 50 µg | EUR 250 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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20-abx107303 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-100g | Abbexa | 100 µg | EUR 362.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-20g | Abbexa | 20 µg | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-50g | Abbexa | 50 µg | EUR 250 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-YP362073HQD | Cusabio | 6387 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP71163 | SAB | 1mg | EUR 1978 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP72984 | SAB | each | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP77542 | SAB | 1mg | EUR 1978 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-EP362073HQD | Cusabio | 3389 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-EP362073HQDb0 | Cusabio | 3390 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-100ug | Biomatik Corporation | 100ug | EUR 460.9 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-1mg | Biomatik Corporation | 1mg | EUR 2237.8 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-20ug | Biomatik Corporation | 20ug | EUR 258.7 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial, Biotinylated |
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CSB-EP362073HQD-B | Cusabio | 7058 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial,Biotinylated |
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RPC27677-100ug | Biomatik Corporation | 100ug | EUR 614.3 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial,Biotinylated |
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RPC27677-1mg | Biomatik Corporation | 1mg | EUR 2373.6 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial,Biotinylated |
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RPC27677-20ug | Biomatik Corporation | 20ug | EUR 468 |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-100g | Abbexa | 100 µg | Ask for price |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-20g | Abbexa | 20 µg | EUR 250 |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-50g | Abbexa | 50 µg | EUR 350 |
Genome Polyprotein Antibody |
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20-abx109417 | Abbexa |
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Genome polyprotein Antibody |
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20-abx300967 | Abbexa |
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Genome polyprotein Antibody |
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1-CSB-PA18549A0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA333180LA01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA362073LA01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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CSB-PA4643XA11GSV | Cusabio | 100ul / 50ul | EUR 299 |
Description: Genome polyprotein |
Genome polyprotein Antibody |
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CSB-PA4644XA11GSW | Cusabio | 100ul / 50ul | EUR 299 |
Description: Genome polyprotein |
Genome polyprotein Antibody |
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1-CSB-PA714772LA01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome Polyprotein Antibody |
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abx109417-100l | Abbexa | 100 µl | EUR 162.5 |
Genome polyprotein Antibody |
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abx300967-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody |
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abx300967-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody |
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abx300967-50g | Abbexa | 50 µg | EUR 250 |
Hepatitis C virus genotype 1a Genome polyprotein |
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1-CSB-EP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in E.coli |
Hepatitis C virus genotype 1a Genome polyprotein |
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1-CSB-MP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in Mammalian cell |
Genome polyprotein Antibody (HRP) |
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20-abx109095 | Abbexa |
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Genome polyprotein Antibody (HRP) |
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20-abx300968 | Abbexa |
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Hepatitis C Genome polyprotein |
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1-CSB-RP184674Ba | Cusabio |
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Description: Recombinant Hepatitis C Genome polyprotein expressed in E.coli |
Genome polyprotein Antibody (HRP) |
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abx109095-100l | Abbexa | 100 µl | EUR 162.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (FITC) |
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20-abx107678 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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20-abx300969 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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abx107678-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (FITC) |
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abx107678-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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abx107678-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (FITC) |
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abx300969-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (FITC) |
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abx300969-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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abx300969-50g | Abbexa | 50 µg | EUR 250 |
Genome Polyprotein Antibody (Biotin) |
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20-abx105887 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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20-abx106264 | Abbexa |
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Genome polyprotein Antibody (Biotin) |
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20-abx300970 | Abbexa |
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Genome Polyprotein Antibody (Biotin) |
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abx105887-100g | Abbexa | 100 µg | EUR 362.5 |
Genome Polyprotein Antibody (Biotin) |
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abx105887-20g | Abbexa | 20 µg | EUR 162.5 |
Genome Polyprotein Antibody (Biotin) |
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abx105887-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (Biotin) |
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abx106264-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (Biotin) |
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abx106264-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (Biotin) |
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abx106264-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (Biotin) |
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abx300970-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (Biotin) |
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abx300970-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (Biotin) |
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abx300970-50g | Abbexa | 50 µg | EUR 250 |
Genome Polyprotein Polyclonal Antibody |
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A68253 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A68254 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A56130 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody |
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A56743 | EpiGentek |
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Recombinant Human parechovirus 1 Genome polyprotein |
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CSB-YP734409HCAV | Cusabio | 9748 mg | Ask for price |
Yellow fever virus Genome polyprotein |
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1-CSB-EP365905YAC1 | Cusabio |
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Description: Recombinant Yellow fever virus Genome polyprotein,partial expressed in E.coli |
Genome Polyprotein (HCV-Core) Antibody |
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33487-05111 | AssayPro | 150 ug | EUR 215 |
Recombinant Human Genome polyprotein, His, Yeast-1mg |
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QP7370-ye-1mg | EnQuireBio | 1mg | EUR 2262 |
Recombinant Human Genome polyprotein, His, Yeast-10ug |
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QP7370-ye-10ug | EnQuireBio | 10ug | EUR 283.2 |
Recombinant Human Genome polyprotein, His, Yeast-50ug |
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QP7370-ye-50ug | EnQuireBio | 50ug | EUR 358.8 |
Recombinant Human Genome polyprotein, His, Yeast-100ug |
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QP7370-ye-100ug | EnQuireBio | 100ug | EUR 576 |
Recombinant Human Genome polyprotein, His, Yeast-200ug |
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QP7370-ye-200ug | EnQuireBio | 200ug | EUR 892.8 |
Recombinant Human Genome polyprotein, His, Yeast-500ug |
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QP7370-ye-500ug | EnQuireBio | 500ug | EUR 1447.2 |
Enterovirus 71 Genome polyprotein Antibody |
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20-abx109758 | Abbexa |
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Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA18549B0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA333180LB01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA362073LB01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is HRP conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, HRP conjugated |
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1-CSB-PA714772LB01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is HRP conjugated. Tested in the following application: ELISA |
Enterovirus 71 Genome polyprotein Antibody |
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abx109758-100l | Abbexa | 100 µl | EUR 162.5 |
Recombinant Hepatitis C Genome polyprotein |
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CSB-RP184674Ba | Cusabio | 5430 mg | Ask for price |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA18549C0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA333180LC01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA362073LC01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is FITC conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, FITC conjugated |
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1-CSB-PA714772LC01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is FITC conjugated. Tested in the following application: ELISA |
Recombinant Hepatitis C Genome polyprotein |
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RPC24458-100ug | Biomatik Corporation | 100ug | EUR 721.6 |
Recombinant Hepatitis C Genome polyprotein |
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RPC24458-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA18549D0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA333180LD01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA362073LD01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody, Biotin conjugated |
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1-CSB-PA714772LD01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Biotin conjugated. Tested in the following application: ELISA |
Japanese encephalitis virus Genome polyprotein |
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1-CSB-EP189574Ba | Cusabio |
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Description: Recombinant Japanese encephalitis virus Genome polyprotein,partial expressed in E.coli |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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CSB-EP333180HFD | Cusabio | 3004 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1a Genome polyprotein, partial |
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CSB-MP333180HFD | Cusabio | 4998 mg | Ask for price |
Recombinant Human parechovirus 2 Genome polyprotein, partial |
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CSB-EP529147HXJ | Cusabio | 9583 mg | Ask for price |
Recombinant Human parechovirus 1 Genome polyprotein, partial |
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CSB-EP734409HCAV | Cusabio | 9651 mg | Ask for price |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-1mg |
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QP7370-ec-1mg | EnQuireBio | 1mg | EUR 1958.4 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-10ug |
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QP7370-ec-10ug | EnQuireBio | 10ug | EUR 240 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-50ug |
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QP7370-ec-50ug | EnQuireBio | 50ug | EUR 315.6 |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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20-abx108220 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (HRP) |
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abx108220-100g | Abbexa | 100 µg | EUR 362.5 |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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abx108220-20g | Abbexa | 20 µg | EUR 162.5 |
Enterovirus 71 Genome polyprotein Antibody (HRP) |
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abx108220-50g | Abbexa | 50 µg | EUR 250 |
Recombinant JEV Genome polyprotein (aa 2528-3432) Protein |
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VAng-Wyb3447-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 9926.4 |
Description: Japanese encephalitis virus (strain Jaoars982) Genome polyprotein, recombinant protein. |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-100ug |
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QP7370-ec-100ug | EnQuireBio | 100ug | EUR 489.6 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-200ug |
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QP7370-ec-200ug | EnQuireBio | 200ug | EUR 760.8 |
Recombinant Human Genome polyprotein, His-SUMO, E.coli-500ug |
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QP7370-ec-500ug | EnQuireBio | 500ug | EUR 1272 |
Enterovirus 71 Genome polyprotein Antibody (FITC) |
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20-abx106801 | Abbexa |
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Enterovirus 71 Genome polyprotein Antibody (FITC) |
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abx106801-100g | Abbexa | 100 µg | EUR 362.5 |
Enterovirus 71 Genome polyprotein Antibody (FITC) |
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abx106801-20g | Abbexa | 20 µg | EUR 162.5 |
Enterovirus 71 Genome polyprotein Antibody (FITC) |
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abx106801-50g | Abbexa | 50 µg | EUR 250 |
Anti-CrPV Genome polyprotein Polyclonal Antibody |
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AB1I144 | Antagene | 0.1mg | EUR 399 |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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20-abx105382 | Abbexa |
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Recombinant Zika virus Genome polyprotein, partial |
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CSB-EP3643GOZ3 | Cusabio | 7769 mg | Ask for price |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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abx105382-100g | Abbexa | 100 µg | EUR 362.5 |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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abx105382-20g | Abbexa | 20 µg | EUR 162.5 |
Enterovirus 71 Genome polyprotein Antibody (Biotin) |
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abx105382-50g | Abbexa | 50 µg | EUR 250 |
Hepatitis C virus genotype 1b Genome polyprotein |
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1-CSB-YP530838HVQ(A3) | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial expressed in Yeast |
Hepatitis C virus genotype 1b Genome polyprotein |
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1-CSB-YP530838HVQ(A4) | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1b Genome polyprotein,partial expressed in Yeast |
Porcine Teschovirus 1 Genome Polyprotein Antibody |
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abx345841-100g | Abbexa | 100 µg | Ask for price |
Porcine Teschovirus 1 Genome Polyprotein Antibody |
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abx345841-20g | Abbexa | 20 µg | EUR 250 |
Porcine Teschovirus 1 Genome Polyprotein Antibody |
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abx345841-50g | Abbexa | 50 µg | EUR 350 |
Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68252 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A68255 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56131 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, HRP Conjugated |
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A56744 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68251 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A68256 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56132 | EpiGentek |
|
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Genome Polyprotein Polyclonal Antibody, FITC Conjugated |
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A56745 | EpiGentek |
|
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Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLA | Cusabio | 7385 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLAa2 | Cusabio | 7384 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLAe0 | Cusabio | 7511 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein, partial |
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CSB-EP3114GLAe1 | Cusabio | 7917 mg | Ask for price |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28548-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28548-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28548-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28549-100ug | Biomatik Corporation | 100ug | EUR 801.9 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28549-1mg | Biomatik Corporation | 1mg | EUR 2885.2 |
Recombinant Enterovirus A71 Genome polyprotein,partial |
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RPC28549-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68250 | EpiGentek |
|
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A68257 | EpiGentek |
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56133 | EpiGentek |
|
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Genome Polyprotein Polyclonal Antibody, Biotin Conjugated |
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A56746 | EpiGentek |
|
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Japanese Encephalitis Virus Genome polyprotein Antibody |
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abx345000-100l | Abbexa | 100 µl | EUR 350 |
Japanese Encephalitis Virus Genome polyprotein Antibody |
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abx345000-50l | Abbexa | 50 µl | EUR 250 |
Recombinant Coxsackievirus B3 Genome polyprotein, partial |
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CSB-EP361017CRM1 | Cusabio | 8884 mg | Ask for price |
Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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VAng-Cr6541-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 5751.6 |
Description: YFV Genome polyprotein, partial, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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VAng-Cr6541-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 3657.6 |
Description: YFV Genome polyprotein, partial, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 286-730) |
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VAng-Cr6541-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1083.6 |
Description: YFV Genome polyprotein, partial, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-1mgEcoli | Creative Biolabs | 1 mg (E. coli) | EUR 3408 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-500gEcoli | Creative Biolabs | 500 µg (E. coli) | EUR 2452.8 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant YFV Genome polyprotein Protein (aa 1-101) |
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VAng-Cr6542-50gEcoli | Creative Biolabs | 50 µg (E. coli) | EUR 1693.2 |
Description: YFV Genome polyprotein, recombinant protein. |
Recombinant West Nile virus Genome polyprotein, partial |
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CSB-EP356974WAF2 | Cusabio | 9323 mg | Ask for price |
Genome Polyprotein (HCV-Core) Antibody (Biotin Conjugate) |
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33487-05121 | AssayPro | 150 ug | EUR 315 |
Bovine Viral Diarrhea Virus Genome Polyprotein Antibody |
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abx345377-100tests | Abbexa | 100 tests | EUR 250 |
Recombinant Human parechovirus 2 Genome polyprotein, partial, Biotinylated |
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CSB-EP897051HHAL-B | Cusabio | 10843 mg | Ask for price |
Recombinant Human parechovirus 1 Genome polyprotein, partial, Biotinylated |
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CSB-EP734409HCAV-B | Cusabio | 10800 mg | Ask for price |
Recombinant Hepatitis C virus Genome polyprotein,partial |
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AP72393 | SAB | each | Ask for price |
Recombinant Yellow fever virus Genome polyprotein,partial |
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AP77947 | SAB | 1mg | EUR 2826 |
Recombinant Yellow fever virus Genome polyprotein, partial |
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CSB-EP365905YAC1 | Cusabio | 3485 mg | Ask for price |
Recombinant Yellow fever virus Genome polyprotein,partial |
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RPC22821-100ug | Biomatik Corporation | 100ug | EUR 721.6 |
Recombinant Yellow fever virus Genome polyprotein,partial |
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RPC22821-1mg | Biomatik Corporation | 1mg | EUR 2884.7 |
Recombinant Yellow fever virus Genome polyprotein,partial |
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RPC22821-20ug | Biomatik Corporation | 20ug | EUR 448.1 |
Rhinovirus Type 1A Lysate |
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NAT41626-100 | The Native Antigen Company | 0.1 | EUR 512.85 |
Description: Rhinovirus consists of a non-enveloped capsid containing a positive-sense single-stranded RNA. |
Rhinovirus Type 1A Lysate |
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NAT41626-500 | The Native Antigen Company | 0.5 | EUR 2181.53 |
Description: Rhinovirus consists of a non-enveloped capsid containing a positive-sense single-stranded RNA. |
Recombinant YFV Genome polyprotein (NS4A) Protein (aa 1-3412) |
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VAng-Cr6545-inquire | Creative Biolabs | inquire | Ask for price |
Description: YFV (isolate Uganda/A7094A4/1948) Genome polyprotein (NS4A), recombinant protein. |
Recombinant Dengue virus type 2 Genome polyprotein, partial |
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CSB-YP530838DCF | Cusabio | 7267 mg | Ask for price |
Recombinant Hepatitis C virus genotype 1a (isolate 1) (HCV) Genome polyprotein(E1),partial |
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AP70969 | SAB | 1mg | EUR 2826 |
Recombinant Japanese encephalitis virus Genome polyprotein, partial |
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CSB-EP189574Ba | Cusabio | 2537 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein , partial |
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CSB-YP312464BKX1 | Cusabio | 6140 mg | Ask for price |
Recombinant Classical swine fever virus Genome polyprotein, partial |
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CSB-YP4953GLU | Cusabio | 12085 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein, partial |
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CSB-BP312464BKX1 | Cusabio | 139 mg | Ask for price |
Recombinant Classical swine fever virus Genome polyprotein, partial |
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CSB-BP4334GLU | Cusabio | 10139 mg | Ask for price |
Recombinant St. louis encephalitis virus Genome polyprotein, partial |
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CSB-EP357746SKT | Cusabio | 9322 mg | Ask for price |
Recombinant Classical swine fever virus Genome polyprotein, partial |
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CSB-EP4953GLU | Cusabio | 11663 mg | Ask for price |
Recombinant Bovine viral diarrhea virus Genome polyprotein, partial |
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CSB-EP312464BKX1 | Cusabio | 2704 mg | Ask for price |
OPCA05394-20UG - GENOME POLYPROTEIN Recombinant Protein (isolate 1) |
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OPCA05394-20UG | Aviva Systems Biology | 20ug | EUR 339 |
We show that the diversity of the TCR repertoire is positively associated with a polymorphism in the human leukocyte antigen class I (HLA-I) locus, and decreases with age and cytomegalovirus infection (CMV). In addition, our analysis suggests that HLA-I polymorphism and age independently form the repertoire in healthy people. Our data describes the main determinants of the diversity of the TCR repertoire of humans, and suggest mechanisms underlying evolutionary fitness advantage of HLA-I