Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism
Alcohol use disorder (AUD) demands huge toll on individuals, families, and communities. Genetic factors determine up to 60% of the individual’s risk of developing alcohol habits problematic. AUD effective prevention and treatment requires knowledge of the genes that the predisposition to alcoholism, alcohol plays a role in the response, and / or contribute to the development of addiction. As genetic and behavioral highly tractable model organism and translated, Drosophila melanogaster has proved valuable for uncovering important gene and mechanistic pathways that have clear human orthologs and that helps explain the complexities of addiction.
vinegar flies show very strong face and validity of the mechanistic model for AUDs, allowing a lot of progress in efforts to understand human genetic involvement in this disease. This progress occurs through an approach that basically fall into one of two categories: (1) finding candidate genes through an associate research of the human genome (GWAS), transcriptomics tissue post-mortem from patients AUD, or connection physiologically relevant, then use reverse genetics fly to validate the role of candidate genes and investigate their molecular function in the context of alcohol.
Utilize the flies to find candidate genes through unbiased screen, GWAS, quantitative trait loci analysis, transcriptomics, or the study of a single gene, and then validates their translational role in human genetic survey. In this review, we highlight the utility of Drosophila as a model for alcoholism by surveying recent advances in our understanding of human AUDs generated from various approaches. We summarize the genes preserved in alcohol-related functions between humans and flies. We also provide an insight into some of the advantages and limitations of this approach. Overall, this review shows how Drosophila have and can be used to answer important questions about the genetics of alcoholism.
Genetic and environmental determinants of human TCR repertoire diversity
T cell discrimination of self and non-self is the basis of the adaptive immune response, and is regulated by the interaction between T cell receptors (TCRs) and their cognate ligands presented by major histocompatibility molecules (MHC). However, the impact of host immunogenetic variation on the diversity of the TCR repertoire is still unclear. Here, we analyzed a cohort of 666 individuals with TCR repertoire sequencing.
Recombinant Human rhinovirus 1A Genome polyprotein VP1 |
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MBS9422616-5x05mg | MyBiosource | 5x0.5mg | EUR 5965 |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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CSB-YP326367HQA | Cusabio | 6222 mg | Ask for price |
Recombinant Human rhinovirus 1A Genome polyprotein,partial |
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AP72911 | SAB | each | Ask for price |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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CSB-EP326367HQA | Cusabio | 11613 mg | Ask for price |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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MBS1220686-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 375 |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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MBS1220686-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 275 |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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MBS1220686-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 640 |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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MBS1220686-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 450 |
Recombinant Human rhinovirus 1A Genome polyprotein, partial |
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MBS1220686-05mgYeast | MyBiosource | 0.5mg(Yeast) | EUR 1065 |
Recombinant Human rhinovirus 1A Genome polyprotein,partial |
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RPC25135-100ug | Biomatik Corporation | 100ug | EUR 573.1 |
Recombinant Human rhinovirus 1A Genome polyprotein,partial |
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RPC25135-20ug | Biomatik Corporation | 20ug | EUR 288.8 |
Recombinant Human rhinovirus 14 Genome polyprotein |
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MBS1158398-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1205 |
Recombinant Human rhinovirus 14 Genome polyprotein |
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MBS1158398-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 860 |
Recombinant Human rhinovirus 14 Genome polyprotein |
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MBS1158398-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 995 |
Recombinant Human rhinovirus 14 Genome polyprotein |
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MBS1158398-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1035 |
Recombinant Human rhinovirus 14 Genome polyprotein |
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MBS1158398-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1135 |
Recombinant Human rhinovirus 2 Genome polyprotein |
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MBS1030888-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1205 |
Recombinant Human rhinovirus 2 Genome polyprotein |
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MBS1030888-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 860 |
Recombinant Human rhinovirus 2 Genome polyprotein |
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MBS1030888-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 995 |
Recombinant Human rhinovirus 2 Genome polyprotein |
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MBS1030888-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1030 |
Recombinant Human rhinovirus 2 Genome polyprotein |
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MBS1030888-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1135 |
Recombinant Human rhinovirus 1B Genome polyprotein |
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MBS1154102-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1205 |
Recombinant Human rhinovirus 1B Genome polyprotein |
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MBS1154102-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 855 |
Recombinant Human rhinovirus 1B Genome polyprotein |
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MBS1154102-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 995 |
Recombinant Human rhinovirus 1B Genome polyprotein |
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MBS1154102-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1030 |
Recombinant Human rhinovirus 1B Genome polyprotein |
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MBS1154102-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1130 |
Recombinant Human rhinovirus 3 Genome polyprotein |
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MBS1326793-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 1125 |
Recombinant Human rhinovirus 3 Genome polyprotein |
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MBS1326793-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 860 |
Recombinant Human rhinovirus 3 Genome polyprotein |
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MBS1326793-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 995 |
Recombinant Human rhinovirus 3 Genome polyprotein |
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MBS1326793-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 1120 |
Recombinant Human rhinovirus 3 Genome polyprotein |
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MBS1326793-05mgEColi | MyBiosource | 0.5mg(E-Coli) | EUR 1225 |
Recombinant Human rhinovirus 16 Genome polyprotein |
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MBS1325019-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 1120 |
Recombinant Human rhinovirus 16 Genome polyprotein |
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MBS1325019-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 860 |
Recombinant Human rhinovirus 16 Genome polyprotein |
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MBS1325019-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 995 |
Recombinant Human rhinovirus 16 Genome polyprotein |
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MBS1325019-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 1120 |
Recombinant Human rhinovirus 16 Genome polyprotein |
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MBS1325019-05mgEColi | MyBiosource | 0.5mg(E-Coli) | EUR 1225 |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-YP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in Yeast |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQD | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Human rhinovirus A serotype 89 Genome polyprotein |
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1-CSB-EP362073HQDb0 | Cusabio |
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Description: Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial expressed in E.coli |
Recombinant Human rhinovirus 1B Genome polyprotein, partial |
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CSB-EP320160HQB | Cusabio | 10401 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein |
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MBS9422687-002mg | MyBiosource | 0.02mg | EUR 320 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein |
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MBS9422687-01mg | MyBiosource | 0.1mg | EUR 540 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein |
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MBS9422687-05mg | MyBiosource | 0.5mg | EUR 1360 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein |
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MBS9422687-5x05mg | MyBiosource | 5x0.5mg | EUR 5965 |
Rhinovirus A serotype 89 Genome polyprotein Antibody |
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20-abx109372 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody |
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abx109372-100l | Abbexa | 100 µl | EUR 162.5 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS1245807-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 255 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS1245807-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 270 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS1245807-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 405 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS1245807-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 450 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS1245807-05mgYeast | MyBiosource | 0.5mg(Yeast) | EUR 1065 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS9421040-002mg | MyBiosource | 0.02mg | EUR 285 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS9421040-01mg | MyBiosource | 0.1mg | EUR 470 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS9421040-1mg | MyBiosource | 1mg | EUR 1785 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein VP1 |
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MBS9421040-5x1mg | MyBiosource | 5x1mg | EUR 7885 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-YP362073HQD | Cusabio | 6387 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP71163 | SAB | 1mg | EUR 1978 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP72984 | SAB | each | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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AP77542 | SAB | 1mg | EUR 1978 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-EP362073HQD | Cusabio | 3389 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial |
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CSB-EP362073HQDb0 | Cusabio | 3390 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-100ug | Biomatik Corporation | 100ug | EUR 460.9 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-1mg | Biomatik Corporation | 1mg | EUR 2237.8 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial |
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RPC22779-20ug | Biomatik Corporation | 20ug | EUR 258.7 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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20-abx108723 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-100g | Abbexa | 100 µg | EUR 362.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-20g | Abbexa | 20 µg | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (HRP) |
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abx108723-50g | Abbexa | 50 µg | EUR 250 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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20-abx107303 | Abbexa |
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Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-100g | Abbexa | 100 µg | EUR 362.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-20g | Abbexa | 20 µg | EUR 162.5 |
Rhinovirus A serotype 89 Genome polyprotein Antibody (FITC) |
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abx107303-50g | Abbexa | 50 µg | EUR 250 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial, Biotinylated |
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CSB-EP362073HQD-B | Cusabio | 7058 mg | Ask for price |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial,Biotinylated |
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RPC27677-100ug | Biomatik Corporation | 100ug | EUR 614.3 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial,Biotinylated |
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RPC27677-1mg | Biomatik Corporation | 1mg | EUR 2373.6 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein,partial,Biotinylated |
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RPC27677-20ug | Biomatik Corporation | 20ug | EUR 468 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial, Biotinylated |
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MBS7137014-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 255 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial, Biotinylated |
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MBS7137014-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 405 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial, Biotinylated |
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MBS7137014-1mgEColi | MyBiosource | 1mg(E-Coli) | EUR 1425 |
Recombinant Human rhinovirus A serotype 89 Genome polyprotein, partial, Biotinylated |
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MBS7137014-5x1mgEColi | MyBiosource | 5x1mg(E-Coli) | EUR 6215 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody |
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MBS1493993-005mg | MyBiosource | 0.05mg | EUR 190 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody |
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MBS1493993-01mg | MyBiosource | 0.1mg | EUR 270 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody |
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MBS1493993-5x01mg | MyBiosource | 5x0.1mg | EUR 1205 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, FITC |
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MBS1492262-005mg | MyBiosource | 0.05mg | EUR 190 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, FITC |
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MBS1492262-01mg | MyBiosource | 0.1mg | EUR 270 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, FITC |
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MBS1492262-5x01mg | MyBiosource | 5x0.1mg | EUR 1205 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, HRP conjugated |
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MBS1492051-005mg | MyBiosource | 0.05mg | EUR 190 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, HRP conjugated |
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MBS1492051-01mg | MyBiosource | 0.1mg | EUR 270 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, HRP conjugated |
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MBS1492051-5x01mg | MyBiosource | 5x0.1mg | EUR 1205 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, Biotin conjugated |
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MBS1496260-005mg | MyBiosource | 0.05mg | EUR 190 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, Biotin conjugated |
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MBS1496260-01mg | MyBiosource | 0.1mg | EUR 270 |
Rabbit anti-Human rhinovirus A serotype 89 Genome polyprotein polyclonal Antibody, Biotin conjugated |
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MBS1496260-5x01mg | MyBiosource | 5x0.1mg | EUR 1205 |
Recombinant human Genome polyprotein |
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MBS960928-005mg | MyBiosource | 0.05mg | EUR 695 |
Recombinant human Genome polyprotein |
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MBS960928-02mg | MyBiosource | 0.2mg | EUR 905 |
Recombinant human Genome polyprotein |
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MBS960928-05mg | MyBiosource | 0.5mg | EUR 990 |
Recombinant human Genome polyprotein |
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MBS960928-1mg | MyBiosource | 1mg | EUR 1355 |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-100g | Abbexa | 100 µg | Ask for price |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-20g | Abbexa | 20 µg | EUR 250 |
Equine Rhinitis A Virus Genome Polyprotein Antibody |
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abx345840-50g | Abbexa | 50 µg | EUR 350 |
Genome Polyprotein Antibody |
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20-abx109417 | Abbexa |
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Genome polyprotein Antibody |
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20-abx300967 | Abbexa |
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Genome polyprotein Antibody |
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1-CSB-PA18549A0Rb | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Dengue virus. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA333180LA01HFD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Hepatitis C virus genotype 1a. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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1-CSB-PA362073LA01HQD | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human rhinovirus A serotype 89. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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CSB-PA4643XA11GSV | Cusabio | 100ul / 50ul | EUR 299 |
Description: Genome polyprotein |
Genome polyprotein Antibody |
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CSB-PA4644XA11GSW | Cusabio | 100ul / 50ul | EUR 299 |
Description: Genome polyprotein |
Genome polyprotein Antibody |
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1-CSB-PA714772LA01HYH | Cusabio |
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Description: A polyclonal antibody against Genome polyprotein. Recognizes Genome polyprotein from Human enterovirus 71. This antibody is Unconjugated. Tested in the following application: ELISA |
Genome polyprotein Antibody |
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abx300967-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody |
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abx300967-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody |
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abx300967-50g | Abbexa | 50 µg | EUR 250 |
Genome Polyprotein Antibody |
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abx109417-100l | Abbexa | 100 µl | EUR 162.5 |
Genome polyprotein Antibody |
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MBS7147310-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS7149174-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS7152538-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS7152900-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS7153436-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS7153583-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS7150431-005mL | MyBiosource | 0.05mL | EUR 190 |
Genome polyprotein Antibody |
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MBS7150431-01mL | MyBiosource | 0.1mL | EUR 270 |
Genome polyprotein Antibody |
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MBS7150431-5x01mL | MyBiosource | 5x0.1mL | EUR 1205 |
Genome polyprotein Antibody |
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MBS7165482-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS9004166-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Genome polyprotein Antibody |
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MBS9000495-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Hepatitis C virus genotype 1a Genome polyprotein |
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1-CSB-EP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in E.coli |
Hepatitis C virus genotype 1a Genome polyprotein |
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1-CSB-MP333180HFD | Cusabio |
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Description: Recombinant Hepatitis C virus genotype 1a Genome polyprotein,partial expressed in Mammalian cell |
Recombinant Genome polyprotein |
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MBS1141323-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 875 |
Recombinant Genome polyprotein |
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MBS1141323-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 490 |
Recombinant Genome polyprotein |
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MBS1141323-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 690 |
Recombinant Genome polyprotein |
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MBS1141323-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 640 |
Recombinant Genome polyprotein |
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MBS1141323-05mgEColi | MyBiosource | 0.5mg(E-Coli) | EUR 695 |
Recombinant Genome polyprotein |
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MBS1068339-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 990 |
Recombinant Genome polyprotein |
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MBS1068339-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 555 |
Recombinant Genome polyprotein |
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MBS1068339-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 745 |
Recombinant Genome polyprotein |
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MBS1068339-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 665 |
Recombinant Genome polyprotein |
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MBS1068339-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 870 |
Recombinant Genome polyprotein |
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MBS1257473-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 990 |
Recombinant Genome polyprotein |
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MBS1257473-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 555 |
Recombinant Genome polyprotein |
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MBS1257473-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 745 |
Recombinant Genome polyprotein |
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MBS1257473-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 665 |
Recombinant Genome polyprotein |
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MBS1257473-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 870 |
Recombinant Genome polyprotein |
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MBS1236293-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1045 |
Recombinant Genome polyprotein |
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MBS1236293-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 625 |
Recombinant Genome polyprotein |
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MBS1236293-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 800 |
Recombinant Genome polyprotein |
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MBS1236293-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 725 |
Recombinant Genome polyprotein |
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MBS1236293-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 935 |
Recombinant Genome polyprotein |
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MBS1040920-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1045 |
Recombinant Genome polyprotein |
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MBS1040920-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 620 |
Recombinant Genome polyprotein |
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MBS1040920-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 795 |
Recombinant Genome polyprotein |
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MBS1040920-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 720 |
Recombinant Genome polyprotein |
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MBS1040920-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 930 |
Genome polyprotein Antibody (HRP) |
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20-abx109095 | Abbexa |
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Genome polyprotein Antibody (HRP) |
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20-abx300968 | Abbexa |
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Hepatitis C Genome polyprotein |
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1-CSB-RP184674Ba | Cusabio |
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Description: Recombinant Hepatitis C Genome polyprotein expressed in E.coli |
Genome polyprotein Antibody (HRP) |
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abx300968-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (HRP) |
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abx300968-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (HRP) |
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abx109095-100l | Abbexa | 100 µl | EUR 162.5 |
Recombinant Human enterovirus 70 Genome polyprotein |
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MBS1260910-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1195 |
Recombinant Human enterovirus 70 Genome polyprotein |
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MBS1260910-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 845 |
Recombinant Human enterovirus 70 Genome polyprotein |
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MBS1260910-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 985 |
Recombinant Human enterovirus 70 Genome polyprotein |
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MBS1260910-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1015 |
Recombinant Human enterovirus 70 Genome polyprotein |
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MBS1260910-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1120 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1327007-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1200 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1327007-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 850 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1327007-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 990 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1327007-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1020 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1327007-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1125 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1427939-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1200 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1427939-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 850 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1427939-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 990 |
Recombinant Human enterovirus 71 Genome polyprotein |
|||
MBS1427939-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 1020 |
Recombinant Human enterovirus 71 Genome polyprotein |
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MBS1427939-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1125 |
Genome polyprotein Antibody (FITC) |
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20-abx107678 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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20-abx300969 | Abbexa |
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Genome polyprotein Antibody (FITC) |
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abx107678-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (FITC) |
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abx107678-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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abx107678-50g | Abbexa | 50 µg | EUR 250 |
Genome polyprotein Antibody (FITC) |
|||
abx300969-100g | Abbexa | 100 µg | EUR 362.5 |
Genome polyprotein Antibody (FITC) |
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abx300969-20g | Abbexa | 20 µg | EUR 162.5 |
Genome polyprotein Antibody (FITC) |
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abx300969-50g | Abbexa | 50 µg | EUR 250 |
Recombinant Human parechovirus 1 Genome polyprotein |
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CSB-YP734409HCAV | Cusabio | 9748 mg | Ask for price |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1055056-002mgBaculovirus | MyBiosource | 0.02mg(Baculovirus) | EUR 1170 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1055056-002mgEColi | MyBiosource | 0.02mg(E-Coli) | EUR 810 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1055056-002mgYeast | MyBiosource | 0.02mg(Yeast) | EUR 960 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1055056-01mgEColi | MyBiosource | 0.1mg(E-Coli) | EUR 970 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1055056-01mgYeast | MyBiosource | 0.1mg(Yeast) | EUR 1125 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1453047-005mgBaculovirus | MyBiosource | 0.05mg(Baculovirus) | EUR 1120 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1453047-005mgEColi | MyBiosource | 0.05mg(E-Coli) | EUR 810 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1453047-005mgYeast | MyBiosource | 0.05mg(Yeast) | EUR 960 |
Recombinant Human parechovirus 2 Genome polyprotein |
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MBS1453047-02mgEColi | MyBiosource | 0.2mg(E-Coli) | EUR 1080 |
We show that the diversity of the TCR repertoire is positively associated with a polymorphism in the human leukocyte antigen class I (HLA-I) locus, and decreases with age and cytomegalovirus infection (CMV). In addition, our analysis suggests that HLA-I polymorphism and age independently form the repertoire in healthy people. Our data describes the main determinants of the diversity of the TCR repertoire of humans, and suggest mechanisms underlying evolutionary fitness advantage of HLA-I