Tag: crispr v2
A novel BRET based genetic coded biosensor for apoptosis detection at deep tissue level in live animal
ANNEXIN V belongs to a household of phospholipid binding proteins which is ready to bind to negatively charged phospholipids akin to phosphatidylserine (PS) within the presence of a excessive affinity Ca2+ ion. When apoptosis happens, even at early stage, PS shall be uncovered to the surface of the cell floor from the cytoplasm facet of membrane…
Read MoreResponses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice
Placodes are ectodermal thickenings of the embryonic vertebrate head. Their descendants contribute to sensory organ improvement, but additionally give rise to sensory neurons of the cranial nerves. In mammals, the signaling pathways which regulate the morphogenesis and neurogenesis of epibranchial placodes, localized dorsocaudally to the pharyngeal clefts, are poorly understood. Subsequently, we carried out mouse…
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