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Glycolytic Reprogramming in Silica-Induced Lung Macrophages and Silicosis Reversed by Ac-SDKP Treatment

Glycolytic Reprogramming in Silica-Induced Lung Macrophages and Silicosis Reversed by Ac-SDKP Treatment

Glycolytic reprogramming is a crucial metabolic function within the growth of pulmonary fibrosis. Nevertheless, the particular mechanism of glycolysis in silicosis continues to be not clear. On this examine, silicotic fashions and silica-induced macrophage have been used to elucidate the Read more…


Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity

Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity

Serological assays have been broadly employed through the coronavirus illness 2019 (COVID-19) pandemic to measure antibody responses to extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to trace seroconversion in populations. Nevertheless, at present obtainable assays don’t enable willpower of neutralization capability Read more…


Cetuximab-siRNA Conjugate Linked Through Cationized Gelatin Knocks Down KRAS G12C Mutation in NSCLC Sensitizing the Cells Toward Gefitinib

Cetuximab-siRNA Conjugate Linked Through Cationized Gelatin Knocks Down KRAS G12C Mutation in NSCLC Sensitizing the Cells Toward Gefitinib

Supply of small-interfering RNA (siRNA) has been of nice curiosity prior to now decade for efficient gene silencing. To beat artificial and regulatory challenges posed by nanoparticle-mediated siRNA supply, antibody-siRNA conjugate (ARC) platform is rising as a possible siRNA supply Read more…