Argentine Bioethics Association

Description: Description of target: Recombinant Human Ras-Related C3 Botulinum Toxin substrate 1;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.054ng/mL

Description: Description of target: Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. Stimulates PKN2 kinase activity. In concert with RAB7A, plays a role in regulating the formation of RBs (ruffled borders) in osteoclasts. In podocytes, promotes nuclear shuttling of NR3C2; this modulation is required for a proper kidney functioning. Required for atypical chemokine receptor ACKR2-induced LIMK1-PAK1-dependent phosphorylation of cofilin (CFL1) and for up-regulation of ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. In synapses, seems to mediate the regulation of F-actin cluster formation performed by SHANK3.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.060 ng/mL

Description: Description of target: Plasma membrane-associated small gtpase which cycles between active gtp-bound and inactive gdp-bound states. in its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles. rac1 p21/rho gdi heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the nadph oxidase activity in macrophages. essential for the spata13-mediated regulation of cell migration and adhesion assembly and disassembly. stimulates pkn2 kinase activity. in concert with rab7a, plays a role in regulating the formation of rbs (ruffled borders) in osteoclasts. in glioma cells, promotes cell migration and invasion. in podocytes, promotes nuclear shuttling of nr3c2, this modulation is required for a proper kidney functioning. required for atypical chemokine receptor ackr2-induced limk1-pak1-dependent phosphorylation of cofilin (cfl1) and for up-regulation of ackr2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. in synapses, seems to mediate the regulation of f-actin cluster formation performed by shank3.;Species reactivity: Rat;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: <0.069ng/mL

Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.085ng/mL

Description: A polyclonal antibody against RAC1. Recognizes RAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000

Description: A polyclonal antibody against RAC1. Recognizes RAC1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:100-1:1200, IF:1:200-1:500

Description: A polyclonal antibody against RAC1. Recognizes RAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

Description: A polyclonal antibody against RAC1. Recognizes RAC1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;ELISA:1:1000-1:2000, WB:1:200-1:1000