Argentine Bioethics Association

Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Homo sapiens;Sensitivity: 1.875 ng/ml

Description: The substance FTY720 Hydrochloride is a s1p receptor ligand. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mg/ml in DMSO or to 40 mg/ml in ethanol (warmed).

Description: The substance FTY720 Hydrochloride is a s1p receptor ligand. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mg/ml in DMSO or to 40 mg/ml in ethanol (warmed).

Description: Description of target: Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body (PubMed:8910577). May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection (PubMed:8910577). May play a role in chromatin-mediated regulation of gene expression although it does not bind to histone H3 tails (PubMed:24267382).1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More…</a></p> Manual assertion based on opinion iniRef.2"Identification and characterization of a leukocyte-specific component of the nuclear body."_x005F_x005F_x000D_Bloch D.B., de la Monte S.M., Guigaouri P., Filippov A., Bloch K.D._x005F_x005F_x000D_J. Biol. Chem. 271:29198-29204(1996) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SP140), VARIANT LYS-516, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION BY INTERFERON.2 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.2"Identification and characterization of a leukocyte-specific component of the nuclear body."_x005F_x005F_x000D_Bloch D.B., de la Monte S.M., Guigaouri P., Filippov A., Bloch K.D._x005F_x005F_x000D_J. Biol. Chem. 271:29198-29204(1996) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SP140), VARIANT LYS-516, FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION BY INTERFERON.Ref.6"Structure of human Sp140 PHD finger: an atypical fold interacting with Pin1."_x005F_x005F_x000D_Zucchelli C., Tamburri S., Quilici G., Palagano E., Berardi A., Saare M., Peterson P., Bachi A., Musco G._x005F_x005F_x000D_FEBS J. 281:216-231(2014) [PubMed] [Europe PMC] [Abstract]Cited for: STRUCTURE BY NMR OF 687-738, FUNCTION, PHOSPHORYLATION AT THR-726, INTERACTION WITH PIN1. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.053 ng/mL

Description: Description of target: Together with PML, this tumor suppressor is a major constituent of the PML bodies, a subnuclear organelle involved in a large number of physiological processes including cell growth, differentiation and apoptosis. Functions as a transcriptional coactivator of ETS1 and ETS2 Under certain conditions, it may also act as a corepressor of ETS1 preventing its binding to DNA Through the regulation of ETS1 it may play a role in angiogenesis, controlling endothelial cell motility and invasion. Through interaction with the MRN complex it may be involved in the regulation of telomeres lengthening. May also regulate TP53-mediated transcription and through CASP8AP2, regulate FAS-mediated apoptosis. Also plays a role in infection by viruses, including human cytomegalovirus and Epstein-Barr virus, through mechanisms that may involve chromatin and/or transcriptional regulation.;Species reactivity: Human;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.094 ng/mL

Description: The Human SP100 Antibody ELISA kit is designed to detect and quantify the level of human SP100 Antibody in cell culture supernatant, serum, plasma and tissue.